Identity
HGNC
LOCATION
8p22
LOCUSID
ALIAS
HCRP1,PQBP2,SPG53
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 137492
MIM: 609927
HGNC: 24928
Ensembl: ENSG00000155975
Variants:
dbSNP: 137492
ClinVar: 137492
TCGA: ENSG00000155975
COSMIC: VPS37A
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31519728 | 2019 | VPS37A directs ESCRT recruitment for phagophore closure. | 52 |
| 31519728 | 2019 | VPS37A directs ESCRT recruitment for phagophore closure. | 52 |
| 30518879 | 2018 | HCRP-1 regulates EGFR-AKT-BIM-mediated anoikis resistance and serves as a prognostic marker in human colon cancer. | 12 |
| 30518879 | 2018 | HCRP-1 regulates EGFR-AKT-BIM-mediated anoikis resistance and serves as a prognostic marker in human colon cancer. | 12 |
| 28458158 | 2017 | HCRP1 regulates proliferation, invasion, and drug resistance via EGFR signaling in prostate cancer. | 3 |
| 28963677 | 2017 | HCRP1 downregulation confers poor prognosis and induces chemoresistance through regulation of EGFR-AKT pathway in human gastric cancer. | 5 |
| 28458158 | 2017 | HCRP1 regulates proliferation, invasion, and drug resistance via EGFR signaling in prostate cancer. | 3 |
| 28963677 | 2017 | HCRP1 downregulation confers poor prognosis and induces chemoresistance through regulation of EGFR-AKT pathway in human gastric cancer. | 5 |
| 27311861 | 2016 | Decreased HCRP1 promotes breast cancer metastasis by enhancing EGFR phosphorylation. | 6 |
| 27311861 | 2016 | Decreased HCRP1 promotes breast cancer metastasis by enhancing EGFR phosphorylation. | 6 |
| 22891969 | 2013 | HCRP1 expression status is a significant prognostic marker in oral and oropharyngeal cancer. | 7 |
| 22891969 | 2013 | HCRP1 expression status is a significant prognostic marker in oral and oropharyngeal cancer. | 7 |
| 22717650 | 2012 | A founder mutation in Vps37A causes autosomal recessive complex hereditary spastic paraparesis. | 33 |
| 22717650 | 2012 | A founder mutation in Vps37A causes autosomal recessive complex hereditary spastic paraparesis. | 33 |
| 22016507 | 2011 | hVps37A Status affects prognosis and cetuximab sensitivity in ovarian cancer. | 13 |
Citation
Dessen P
VPS37A (VPS37A subunit of ESCRT-I)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/40605/vps37a
