Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2326
MIM: 136130
HGNC: 3769
Ensembl: ENSG00000010932
Variants:
dbSNP: 2326
ClinVar: 2326
TCGA: ENSG00000010932
COSMIC: FMO1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA450626 | nicotine | Chemical | ClinicalAnnotation | associated | |||
| PA450688 | olanzapine | Chemical | ClinicalAnnotation | associated | PK | 23147717 | |
| PA451581 | tamoxifen | Chemical | Pathway | associated | 23962908 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34509493 | 2021 | Human flavin-containing monooxygenase 1 and its long-sought hydroperoxyflavin intermediate. | 3 |
| 34509493 | 2021 | Human flavin-containing monooxygenase 1 and its long-sought hydroperoxyflavin intermediate. | 3 |
| 30381441 | 2019 | Nicotine-N'-Oxidation by Flavin Monooxygenase Enzymes. | 12 |
| 30381441 | 2019 | Nicotine-N'-Oxidation by Flavin Monooxygenase Enzymes. | 12 |
| 29080679 | 2018 | SFRP2/DPP4 and FMO1/LSP1 Define Major Fibroblast Populations in Human Skin. | 144 |
| 29080679 | 2018 | SFRP2/DPP4 and FMO1/LSP1 Define Major Fibroblast Populations in Human Skin. | 144 |
| 28413702 | 2017 | Targeted sequencing identifies genetic polymorphisms of flavin-containing monooxygenase genes contributing to susceptibility of nicotine dependence in European American and African American. | 4 |
| 28413702 | 2017 | Targeted sequencing identifies genetic polymorphisms of flavin-containing monooxygenase genes contributing to susceptibility of nicotine dependence in European American and African American. | 4 |
| 26839369 | 2016 | Quantification of Flavin-containing Monooxygenases 1, 3, and 5 in Human Liver Microsomes by UPLC-MRM-Based Targeted Quantitative Proteomics and Its Application to the Study of Ontogeny. | 12 |
| 26839369 | 2016 | Quantification of Flavin-containing Monooxygenases 1, 3, and 5 in Human Liver Microsomes by UPLC-MRM-Based Targeted Quantitative Proteomics and Its Application to the Study of Ontogeny. | 12 |
| 23147717 | 2013 | Influence of FMO1 and 3 polymorphisms on serum olanzapine and its N-oxide metabolite in psychiatric patients. | 10 |
| 23147717 | 2013 | Influence of FMO1 and 3 polymorphisms on serum olanzapine and its N-oxide metabolite in psychiatric patients. | 10 |
| 21082301 | 2011 | Flavin-containing monooxygenase mRNA levels are up-regulated in als brain areas in SOD1-mutant mice. | 2 |
| 21540762 | 2011 | Common polymorphisms in FMO1 are associated with nicotine dependence. | 10 |
| 21082301 | 2011 | Flavin-containing monooxygenase mRNA levels are up-regulated in als brain areas in SOD1-mutant mice. | 2 |
Citation
Dessen P
FMO1 (flavin containing dimethylaniline monoxygenase 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/40614/fmo1
