Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2330
MIM: 603957
HGNC: 3773
Ensembl: ENSG00000131781
Variants:
dbSNP: 2330
ClinVar: 2330
TCGA: ENSG00000131781
COSMIC: FMO5
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Drug metabolism - cytochrome P450 | KEGG | ko00982 |
| Drug metabolism - cytochrome P450 | KEGG | hsa00982 |
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA443886 | Diabetes Mellitus | Disease | ClinicalAnnotation | associated | PD | 26306225 | |
| PA450395 | metformin | Chemical | ClinicalAnnotation | associated | PD | 26306225 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 28783300 | 2017 | Baeyer-Villiger Monooxygenase FMO5 as Entry Point in Drug Metabolism. | 9 |
| 28783300 | 2017 | Baeyer-Villiger Monooxygenase FMO5 as Entry Point in Drug Metabolism. | 9 |
| 26771671 | 2016 | Biocatalytic Characterization of Human FMO5: Unearthing Baeyer-Villiger Reactions in Humans. | 16 |
| 26839369 | 2016 | Quantification of Flavin-containing Monooxygenases 1, 3, and 5 in Human Liver Microsomes by UPLC-MRM-Based Targeted Quantitative Proteomics and Its Application to the Study of Ontogeny. | 12 |
| 26771671 | 2016 | Biocatalytic Characterization of Human FMO5: Unearthing Baeyer-Villiger Reactions in Humans. | 16 |
| 26839369 | 2016 | Quantification of Flavin-containing Monooxygenases 1, 3, and 5 in Human Liver Microsomes by UPLC-MRM-Based Targeted Quantitative Proteomics and Its Application to the Study of Ontogeny. | 12 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 19834535 | 2009 | Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging. | 29 |
| 19898482 | 2009 | Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy. | 105 |
| 19834535 | 2009 | Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging. | 29 |
| 19898482 | 2009 | Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy. | 105 |
| 16183778 | 2006 | Quantitative analysis of FMO gene mRNA levels in human tissues. | 41 |
| 16183778 | 2006 | Quantitative analysis of FMO gene mRNA levels in human tissues. | 41 |
Citation
Dessen P
FMO5 (flavin containing dimethylaniline monoxygenase 5)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/40615/fmo5
