Identity
HGNC
LOCATION
8p11.21
LOCUSID
ALIAS
FPTA,PGGT1A,PTAR2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2339
MIM: 134635
HGNC: 3782
Ensembl: ENSG00000168522
Variants:
dbSNP: 2339
ClinVar: 2339
TCGA: ENSG00000168522
COSMIC: FNTA
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33112492 | 2021 | Cell-permeable CaaX-peptides affect K-Ras downstream signaling and promote cell death in cancer cells. | 7 |
| 34315531 | 2021 | Protein farnesylation is upregulated in Alzheimer's human brains and neuron-specific suppression of farnesyltransferase mitigates pathogenic processes in Alzheimer's model mice. | 12 |
| 33112492 | 2021 | Cell-permeable CaaX-peptides affect K-Ras downstream signaling and promote cell death in cancer cells. | 7 |
| 34315531 | 2021 | Protein farnesylation is upregulated in Alzheimer's human brains and neuron-specific suppression of farnesyltransferase mitigates pathogenic processes in Alzheimer's model mice. | 12 |
| 33257571 | 2020 | Scaffold association factor B (SAFB) is required for expression of prenyltransferases and RAS membrane association. | 5 |
| 33257571 | 2020 | Scaffold association factor B (SAFB) is required for expression of prenyltransferases and RAS membrane association. | 5 |
| 28948621 | 2017 | Exploring the putative self-binding property of the human farnesyltransferase alpha-subunit. | 3 |
| 29198824 | 2017 | Inhibition of Farnesyltransferase Potentiates NOTCH-Targeted Therapy against Glioblastoma Stem Cells. | 13 |
| 28948621 | 2017 | Exploring the putative self-binding property of the human farnesyltransferase alpha-subunit. | 3 |
| 29198824 | 2017 | Inhibition of Farnesyltransferase Potentiates NOTCH-Targeted Therapy against Glioblastoma Stem Cells. | 13 |
| 22160308 | 2012 | Geranylgeranyl transferase 1 modulates autophagy and apoptosis in human airway smooth muscle. | 29 |
| 22160308 | 2012 | Geranylgeranyl transferase 1 modulates autophagy and apoptosis in human airway smooth muscle. | 29 |
| 19841875 | 2010 | Polymorphisms of the lamina maturation pathway and their association with the metabolic syndrome: the DESIR prospective study. | 2 |
| 20403997 | 2010 | Genetic variation in 3-hydroxy-3-methylglutaryl CoA reductase modifies the chemopreventive activity of statins for colorectal cancer. | 35 |
| 19841875 | 2010 | Polymorphisms of the lamina maturation pathway and their association with the metabolic syndrome: the DESIR prospective study. | 2 |
Citation
Dessen P
FNTA (farnesyltransferase, CAAX box, alpha)
Atlas Genet Cytogenet Oncol Haematol. 2004-02-01
Online version: http://atlasgeneticsoncology.org/gene/40618/fnta
