G0S2 (G0/G1 switch 2)

2003-11-01  

Identity

HGNC
G0S2
LOCATION
1q32.2
LOCUSID
50486
ALIAS
-

Other Information

Locus ID:

NCBI: 50486
MIM: 614447
HGNC: 30229
Ensembl: ENSG00000123689

Variants:

dbSNP: 50486
ClinVar: 50486
TCGA: ENSG00000123689
COSMIC: G0S2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000123689ENST00000367029P27469

Expression (GTEx)

0
100
200
300
400
500
600
700
800
900
1000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Fatty acid, triacylglycerol, and ketone body metabolismREACTOMER-HSA-535734
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)REACTOMER-HSA-400206
PPARA activates gene expressionREACTOMER-HSA-1989781

References

Pubmed IDYearTitleCitations
198786462023ATXN3 controls DNA replication and transcription by regulating chromatin structure.24
363668422023Gastric Cancer Growth Modulated by circSNTB2/miR-6938-5p/G0S2 and PDCD4.0
198786462023ATXN3 controls DNA replication and transcription by regulating chromatin structure.24
363668422023Gastric Cancer Growth Modulated by circSNTB2/miR-6938-5p/G0S2 and PDCD4.0
365364772022Loss of G0/G1 switch gene 2 (G0S2) promotes disease progression and drug resistance in chronic myeloid leukaemia (CML) by disrupting glycerophospholipid metabolism.4
365364772022Loss of G0/G1 switch gene 2 (G0S2) promotes disease progression and drug resistance in chronic myeloid leukaemia (CML) by disrupting glycerophospholipid metabolism.4
335459272021Low G0S2 gene expression levels in peripheral blood may be a genetic marker of acute myocardial infarction in patients with stable coronary atherosclerotic disease: A retrospective clinical study.4
335459272021Low G0S2 gene expression levels in peripheral blood may be a genetic marker of acute myocardial infarction in patients with stable coronary atherosclerotic disease: A retrospective clinical study.4
321713352020An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci.45
321713352020An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci.45
307703522019Targeted Assessment of G0S2 Methylation Identifies a Rapidly Recurrent, Routinely Fatal Molecular Subtype of Adrenocortical Carcinoma.31
308021542019Identification of an intrinsic lysophosphatidic acid acyltransferase activity in the lipolytic inhibitor G(0)/G(1) switch gene 2 (G0S2).10
313714512019A molecular triage process mediated by RING finger protein 126 and BCL2-associated athanogene 6 regulates degradation of G(0)/G(1) switch gene 2.8
307703522019Targeted Assessment of G0S2 Methylation Identifies a Rapidly Recurrent, Routinely Fatal Molecular Subtype of Adrenocortical Carcinoma.31
308021542019Identification of an intrinsic lysophosphatidic acid acyltransferase activity in the lipolytic inhibitor G(0)/G(1) switch gene 2 (G0S2).10

Citation

Dessen P

G0S2 (G0/G1 switch 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/40660