GPR132 (G protein-coupled receptor 132)

2003-02-01  

Identity

HGNC
LOCATION
14q32.33
LOCUSID
ALIAS
G2A

Other Information

Locus ID:

NCBI: 29933
MIM: 606167
HGNC: 17482
Ensembl: ENSG00000183484

Variants:

dbSNP: 29933
ClinVar: 29933
TCGA: ENSG00000183484
COSMIC: GPR132

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000183484ENST00000329797Q9UNW8
ENSG00000183484ENST00000392585Q9UNW8
ENSG00000183484ENST00000539291Q9UNW8
ENSG00000183484ENST00000549990A0A0G2JL29
ENSG00000183484ENST00000551869F8VRH8

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class A/1 (Rhodopsin-like receptors)REACTOMER-HSA-373076
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (q) signalling eventsREACTOMER-HSA-416476
Gastrin-CREB signalling pathway via PKC and MAPKREACTOMER-HSA-881907

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
364372472022Activation of orphan receptor GPR132 induces cell differentiation in acute myeloid leukemia.2
364372472022Activation of orphan receptor GPR132 induces cell differentiation in acute myeloid leukemia.2
339416542021Lipid Receptor G2A-Mediated Signal Pathway Plays a Critical Role in Inflammatory Response by Promoting Classical Macrophage Activation.3
339416542021Lipid Receptor G2A-Mediated Signal Pathway Plays a Critical Role in Inflammatory Response by Promoting Classical Macrophage Activation.3
329487832020Expression profiles of proton-sensing G-protein coupled receptors in common skin tumors.9
329487832020Expression profiles of proton-sensing G-protein coupled receptors in common skin tumors.9
280498472017Gpr132 sensing of lactate mediates tumor-macrophage interplay to promote breast cancer metastasis.201
280498472017Gpr132 sensing of lactate mediates tumor-macrophage interplay to promote breast cancer metastasis.201
270495922016Heteromerization of G2A and OGR1 enhances proton sensitivity and proton-induced calcium signals.14
275884742016Direct interaction of Ikaros and Foxp1 modulates expression of the G protein-coupled receptor G2A in B-lymphocytes and acute lymphoblastic leukemia.6
270495922016Heteromerization of G2A and OGR1 enhances proton sensitivity and proton-induced calcium signals.14
275884742016Direct interaction of Ikaros and Foxp1 modulates expression of the G protein-coupled receptor G2A in B-lymphocytes and acute lymphoblastic leukemia.6
198550982010Identification and analysis of two splice variants of human G2A generated by alternative splicing.6
198550982010Identification and analysis of two splice variants of human G2A generated by alternative splicing.6
199489752009Integrative predictive model of coronary artery calcification in atherosclerosis.16

Citation

Dessen P

GPR132 (G protein-coupled receptor 132)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40740/gpr132