Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2888
MIM: 601524
HGNC: 4565
Ensembl: ENSG00000115290
Variants:
dbSNP: 2888
ClinVar: 2888
TCGA: ENSG00000115290
COSMIC: GRB14
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000115290 | ENST00000263915 | Q14449 |
| ENSG00000115290 | ENST00000424693 | C9JLT6 |
| ENSG00000115290 | ENST00000446413 | C9JD37 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Hemostasis | REACTOME | R-HSA-109582 |
| Cell surface interactions at the vascular wall | REACTOME | R-HSA-202733 |
| Tie2 Signaling | REACTOME | R-HSA-210993 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35955692 | 2022 | Metabolic Effects of the Waist-To-Hip Ratio Associated Locus GRB14/COBLL1 Are Related to GRB14 Expression in Adipose Tissue. | 1 |
| 35955692 | 2022 | Metabolic Effects of the Waist-To-Hip Ratio Associated Locus GRB14/COBLL1 Are Related to GRB14 Expression in Adipose Tissue. | 1 |
| 33867829 | 2021 | Identification of low-dose radiation-induced exosomal circ-METRN and miR-4709-3p/GRB14/PDGFRα pathway as a key regulatory mechanism in Glioblastoma progression and radioresistance: Functional validation and clinical theranostic significance. | 26 |
| 33867829 | 2021 | Identification of low-dose radiation-induced exosomal circ-METRN and miR-4709-3p/GRB14/PDGFRα pathway as a key regulatory mechanism in Glioblastoma progression and radioresistance: Functional validation and clinical theranostic significance. | 26 |
| 31347216 | 2019 | Dephosphorylation of clustered phosphoserine residues in human Grb14 by protein phosphatase 1 and its effect on insulin receptor complex formation. | 0 |
| 31347216 | 2019 | Dephosphorylation of clustered phosphoserine residues in human Grb14 by protein phosphatase 1 and its effect on insulin receptor complex formation. | 0 |
| 28130417 | 2017 | Phosphorylation of clustered serine residues in the N-terminus of BPS domain negatively regulates formation of the complex between human Grb14 and insulin receptor. | 4 |
| 28295264 | 2017 | The adaptors Grb10 and Grb14 are calmodulin-binding proteins. | 5 |
| 28130417 | 2017 | Phosphorylation of clustered serine residues in the N-terminus of BPS domain negatively regulates formation of the complex between human Grb14 and insulin receptor. | 4 |
| 28295264 | 2017 | The adaptors Grb10 and Grb14 are calmodulin-binding proteins. | 5 |
| 26965150 | 2016 | High expression of growth factor receptor-bound protein 14 predicts poor prognosis for colorectal cancer patients. | 5 |
| 27281273 | 2016 | Air pollution and diabetes association: Modification by type 2 diabetes genetic risk score. | 18 |
| 26965150 | 2016 | High expression of growth factor receptor-bound protein 14 predicts poor prognosis for colorectal cancer patients. | 5 |
| 27281273 | 2016 | Air pollution and diabetes association: Modification by type 2 diabetes genetic risk score. | 18 |
| 23670221 | 2014 | Fat depot-specific mRNA expression of novel loci associated with waist-hip ratio. | 17 |
Citation
Dessen P
GRB14 (growth factor receptor bound protein 14)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/40749/grb14
