GTSE1 (G2 and S-phase expressed 1)

2003-02-01  

Identity

HGNC
GTSE1
LOCATION
22q13.31
LOCUSID
51512
ALIAS
B99
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51512
MIM: 607477
HGNC: 13698
Ensembl: ENSG00000075218

Variants:

dbSNP: 51512
ClinVar: 51512
TCGA: ENSG00000075218
COSMIC: GTSE1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000075218ENST00000454366Q9NYZ3

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
p53 signaling pathwayKEGGko04115
p53 signaling pathwayKEGGhsa04115
Cell CycleREACTOMER-HSA-1640170
Cell Cycle CheckpointsREACTOMER-HSA-69620
G2/M CheckpointsREACTOMER-HSA-69481
Cell Cycle, MitoticREACTOMER-HSA-69278
Mitotic G2-G2/M phasesREACTOMER-HSA-453274
G2/M TransitionREACTOMER-HSA-69275
The role of GTSE1 in G2/M progression after G2 checkpointREACTOMER-HSA-8852276

References

Pubmed IDYearTitleCitations
387153802024GTSE1: A potential prognostic and diagnostic biomarker in various tumors including lung adenocarcinoma.1
387153802024GTSE1: A potential prognostic and diagnostic biomarker in various tumors including lung adenocarcinoma.1
333285782021GTSE1 promotes prostate cancer cell proliferation via the SP1/FOXM1 signaling pathway.15
333330092021Destabilization of Long Astral Microtubules via Cdk1-Dependent Removal of GTSE1 from Their Plus Ends Facilitates Prometaphase Spindle Orientation.12
338805902021GTSE1 promotes SNAIL1 degradation by facilitating its nuclear export in hepatocellular carcin oma cells.5
339743322021G2 and S phase-expressed-1 acts as a putative tumor promoter in cervical cancer by enhancing Wnt/β-catenin signaling via modulation of GSK-3β.4
340077842021GTSE1 Facilitates the Malignant Phenotype of Lung Cancer Cells via Activating AKT/mTOR Signaling.9
342841442021MiR-509-3-5p inhibits colon cancer malignancy by suppressing GTSE1.4
344825922021Downregulation of GTSE1 leads to the inhibition of proliferation, migration, and Warburg effect in cervical cancer by blocking LHDA expression.5
348761702021GTSE1 is possibly involved in the DNA damage repair and cisplatin resistance in osteosarcoma.7
333285782021GTSE1 promotes prostate cancer cell proliferation via the SP1/FOXM1 signaling pathway.15
333330092021Destabilization of Long Astral Microtubules via Cdk1-Dependent Removal of GTSE1 from Their Plus Ends Facilitates Prometaphase Spindle Orientation.12
338805902021GTSE1 promotes SNAIL1 degradation by facilitating its nuclear export in hepatocellular carcin oma cells.5
339743322021G2 and S phase-expressed-1 acts as a putative tumor promoter in cervical cancer by enhancing Wnt/β-catenin signaling via modulation of GSK-3β.4
340077842021GTSE1 Facilitates the Malignant Phenotype of Lung Cancer Cells via Activating AKT/mTOR Signaling.9

Citation

Dessen P

GTSE1 (G2 and S-phase expressed 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40782/css/card-gene.css