HIC2 (HIC ZBTB transcriptional repressor 2)

2003-02-01  

Identity

HGNC
LOCATION
22q11.21
LOCUSID
ALIAS
HRG22,ZBTB30,ZNF907

Other Information

Locus ID:

NCBI: 23119
MIM: 607712
HGNC: 18595
Ensembl: ENSG00000169635

Variants:

dbSNP: 23119
ClinVar: 23119
TCGA: ENSG00000169635
COSMIC: HIC2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000169635ENST00000407464Q96JB3
ENSG00000169635ENST00000407598Q96JB3
ENSG00000169635ENST00000443632Q96JB3

Expression (GTEx)

0
5
10
15
20

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
383641092024let-7 miRNAs repress HIC2 to regulate BCL11A transcription and hemoglobin switching.1
383641092024let-7 miRNAs repress HIC2 to regulate BCL11A transcription and hemoglobin switching.1
366509532023Hypermethylation of HIC2 is a potential prognostic biomarker and tumor suppressor of glioma based on bioinformatics analysis and experiments.2
366509532023Hypermethylation of HIC2 is a potential prognostic biomarker and tumor suppressor of glioma based on bioinformatics analysis and experiments.2
359411872022HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription.11
359411872022HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription.11
311278672019HIC2, a new transcription activator of SIRT1.7
311278672019HIC2, a new transcription activator of SIRT1.7
247485412014HIC2 is a novel dosage-dependent regulator of cardiac development located within the distal 22q11 deletion syndrome region.18
247485412014HIC2 is a novel dosage-dependent regulator of cardiac development located within the distal 22q11 deletion syndrome region.18
115547462001Characterization of HRG22, a human homologue of the putative tumor suppressor gene HIC1.17
115547462001Characterization of HRG22, a human homologue of the putative tumor suppressor gene HIC1.17

Citation

Dessen P

HIC2 (HIC ZBTB transcriptional repressor 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40820/hic2