Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3099
MIM: 601125
HGNC: 4923
Ensembl: ENSG00000159399
Variants:
dbSNP: 3099
ClinVar: 3099
TCGA: ENSG00000159399
COSMIC: HK2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000159399 | ENST00000290573 | P52789 |
| ENSG00000159399 | ENST00000409174 | E9PB90 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37930472 | 2024 | PDLIM1 interacts with HK2 to promote gastric cancer progression through enhancing the Warburg effect via Wnt/β-catenin signaling. | 1 |
| 38224486 | 2024 | The effect and mechanism of hexokinase-2 on cisplatin resistance in lung cancer cells A549. | 0 |
| 38325141 | 2024 | A gain of function mutation in AKT1 increases hexokinase 2 and diminishes oxidative stress in meningioma. | 0 |
| 38682208 | 2024 | Activation of the MEK/ERK Pathway Mediates the Inhibitory Effects of Silvestrol on Nasopharyngeal Carcinoma Cells via RAP1A, HK2, and GADD45A. | 0 |
| 38795416 | 2024 | HK2 and LDHA upregulation mediate hexavalent chromium-induced carcinogenesis, cancer development and prognosis through miR-218 inhibition. | 0 |
| 37930472 | 2024 | PDLIM1 interacts with HK2 to promote gastric cancer progression through enhancing the Warburg effect via Wnt/β-catenin signaling. | 1 |
| 38224486 | 2024 | The effect and mechanism of hexokinase-2 on cisplatin resistance in lung cancer cells A549. | 0 |
| 38325141 | 2024 | A gain of function mutation in AKT1 increases hexokinase 2 and diminishes oxidative stress in meningioma. | 0 |
| 38682208 | 2024 | Activation of the MEK/ERK Pathway Mediates the Inhibitory Effects of Silvestrol on Nasopharyngeal Carcinoma Cells via RAP1A, HK2, and GADD45A. | 0 |
| 38795416 | 2024 | HK2 and LDHA upregulation mediate hexavalent chromium-induced carcinogenesis, cancer development and prognosis through miR-218 inhibition. | 0 |
| 36546770 | 2023 | microRNA-143 interferes the EGFR-stimulated glucose metabolism to re-sensitize 5-FU resistant colon cancer cells via targeting hexokinase 2. | 1 |
| 36548909 | 2023 | LncRNA-SNHG1 promotes paclitaxel resistance of gastric cancer cells through modulating the miR-216b-5p-hexokianse 2 axis. | 6 |
| 36708044 | 2023 | L1CAM promotes vasculogenic mimicry formation by miR-143-3p-induced expression of hexokinase 2 in glioma. | 5 |
| 36793034 | 2023 | Hexokinase 2-mediated glycolysis supports inflammatory responses to Porphyromonas gingivalis in gingival fibroblasts. | 1 |
| 36809521 | 2023 | Hsa_circ_0000591 drives osteosarcoma glycolysis and progression by sequestering miR-194-5p and elevating HK2 expression. | 1 |
Citation
Dessen P
HK2 (hexokinase 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/40827/hk2
