Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3249
MIM: 142440
HGNC: 5155
Ensembl: ENSG00000105707
Variants:
dbSNP: 3249
ClinVar: 3249
TCGA: ENSG00000105707
COSMIC: HPN
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37872868 | 2024 | Hepsin promotes breast tumor growth signaling via the TGFβ-EGFR axis. | 1 |
| 37872868 | 2024 | Hepsin promotes breast tumor growth signaling via the TGFβ-EGFR axis. | 1 |
| 36802168 | 2023 | Spatial position is a key determinant of N-glycan functionality of the scavenger receptor cysteine-rich domain of human hepsin. | 0 |
| 37013685 | 2023 | N-glycosylation mediated folding and quality control in serine proteases of the hepsin family. | 1 |
| 36802168 | 2023 | Spatial position is a key determinant of N-glycan functionality of the scavenger receptor cysteine-rich domain of human hepsin. | 0 |
| 37013685 | 2023 | N-glycosylation mediated folding and quality control in serine proteases of the hepsin family. | 1 |
| 35164791 | 2022 | The POR rs10954732 polymorphism decreases susceptibility to hepatocellular carcinoma and hepsin as a prognostic biomarker correlated with immune infiltration based on proteomics. | 3 |
| 35484884 | 2022 | Silencing of hepsin and inosine 5-monophosphate dehydrogenase 2 by siRNA reduces prostate cancer cells proliferation. | 0 |
| 35164791 | 2022 | The POR rs10954732 polymorphism decreases susceptibility to hepatocellular carcinoma and hepsin as a prognostic biomarker correlated with immune infiltration based on proteomics. | 3 |
| 35484884 | 2022 | Silencing of hepsin and inosine 5-monophosphate dehydrogenase 2 by siRNA reduces prostate cancer cells proliferation. | 0 |
| 33300264 | 2021 | Hepsin: a multifunctional transmembrane serine protease in pathobiology. | 13 |
| 33461973 | 2021 | Oncogenic Ras Disrupts Epithelial Integrity by Activating the Transmembrane Serine Protease Hepsin. | 6 |
| 34131022 | 2021 | The transmembrane serine protease hepsin suppresses type I interferon induction by cleaving STING. | 8 |
| 33300264 | 2021 | Hepsin: a multifunctional transmembrane serine protease in pathobiology. | 13 |
| 33461973 | 2021 | Oncogenic Ras Disrupts Epithelial Integrity by Activating the Transmembrane Serine Protease Hepsin. | 6 |
Citation
Dessen P
HPN (hepsin)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/40857/hpn
