Identity
HGNC
LOCATION
6p21.1
LOCUSID
ALIAS
D6S182,HSP84,HSP90B,HSPC2,HSPCB
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3326
MIM: 140572
HGNC: 5258
Ensembl: ENSG00000096384
Variants:
dbSNP: 3326
ClinVar: 3326
TCGA: ENSG00000096384
COSMIC: HSP90AB1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA130232992 | bevacizumab | Chemical | ClinicalAnnotation | associated | PD | 29871907 | |
| PA444552 | Hypertension | Disease | ClinicalAnnotation | associated | PD | 29871907 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38416826 | 2024 | HSP90β controls NLRP3 autoactivation. | 0 |
| 38416826 | 2024 | HSP90β controls NLRP3 autoactivation. | 0 |
| 37028636 | 2023 | Despite their structural similarities, the cytosolic isoforms of human Hsp90 show different behaviour in thermal unfolding due to their conformation: An FTIR study. | 0 |
| 37406487 | 2023 | Proliferation, migration, and resistance to oxidative and thermal stresses of HT1080 cells with knocked out genes encoding Hsp90α and Hsp90β. | 2 |
| 37415147 | 2023 | PARP1 negatively regulates transcription of BLM through its interaction with HSP90AB1 in prostate cancer. | 0 |
| 37487085 | 2023 | HSP90β prevents aging-related cataract formation through regulation of the charged multivesicular body protein (CHMP4B) and p53. | 1 |
| 37729687 | 2023 | Dissecting the functional significance of HSP90AB1 and other heat shock proteins in countering glioblastomas and ependymomas using omics analysis and drug prediction using virtual screening. | 0 |
| 37028636 | 2023 | Despite their structural similarities, the cytosolic isoforms of human Hsp90 show different behaviour in thermal unfolding due to their conformation: An FTIR study. | 0 |
| 37406487 | 2023 | Proliferation, migration, and resistance to oxidative and thermal stresses of HT1080 cells with knocked out genes encoding Hsp90α and Hsp90β. | 2 |
| 37415147 | 2023 | PARP1 negatively regulates transcription of BLM through its interaction with HSP90AB1 in prostate cancer. | 0 |
| 37487085 | 2023 | HSP90β prevents aging-related cataract formation through regulation of the charged multivesicular body protein (CHMP4B) and p53. | 1 |
| 37729687 | 2023 | Dissecting the functional significance of HSP90AB1 and other heat shock proteins in countering glioblastomas and ependymomas using omics analysis and drug prediction using virtual screening. | 0 |
| 35298351 | 2022 | LncRNA RP3-326I13.1 promotes cisplatin resistance in lung adenocarcinoma by binding to HSP90B and upregulating MMP13. | 5 |
| 35929142 | 2022 | HSP90AB1 Promotes the Proliferation, Migration, and Glycolysis of Head and Neck Squamous Cell Carcinoma. | 6 |
| 36114006 | 2022 | ALS-linked loss of Cyclin-F function affects HSP90. | 3 |
Citation
Dessen P
HSP90AB1 (heat shock protein 90 alpha family class B member 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/40887/hsp90ab1
