Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3352
MIM: 182133
HGNC: 5289
Ensembl: ENSG00000179546
Variants:
dbSNP: 3352
ClinVar: 3352
TCGA: ENSG00000179546
COSMIC: HTR1D
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000179546 | ENST00000374619 | P28221 |
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA172 | GNAI1 | Gene | Pathway | associated | 19741567 | ||
| PA173 | GNAI3 | Gene | Pathway | associated | 19741567 | ||
| PA24347 | GNAI2 | Gene | Pathway | associated | 19741567 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35785570 | 2022 | Knockdown and inhibition of hydroxytryptamine receptor 1D suppress proliferation and migration of gastric cancer cells. | 3 |
| 35813473 | 2022 | HTR1D functions as a key target of HOXA10-AS/miR-340-3p axis to promote the malignant outcome of pancreatic cancer via PI3K-AKT signaling pathway. | 6 |
| 35785570 | 2022 | Knockdown and inhibition of hydroxytryptamine receptor 1D suppress proliferation and migration of gastric cancer cells. | 3 |
| 35813473 | 2022 | HTR1D functions as a key target of HOXA10-AS/miR-340-3p axis to promote the malignant outcome of pancreatic cancer via PI3K-AKT signaling pathway. | 6 |
| 30561038 | 2019 | 5-Hydroxytryptamine Receptor 1D Aggravates Hepatocellular Carcinoma Progression Through FoxO6 in AKT-Dependent and Independent Manners. | 21 |
| 30561038 | 2019 | 5-Hydroxytryptamine Receptor 1D Aggravates Hepatocellular Carcinoma Progression Through FoxO6 in AKT-Dependent and Independent Manners. | 21 |
| 26206285 | 2015 | Altered serotonin (5-HT) 1D and 2A receptor expression may contribute to defective insulin and glucagon secretion in human type 2 diabetes. | 42 |
| 26214021 | 2015 | 5-hydroxytryptamine receptor (5-HT1DR) promotes colorectal cancer metastasis by regulating Axin1/β-catenin/MMP-7 signaling pathway. | 28 |
| 26206285 | 2015 | Altered serotonin (5-HT) 1D and 2A receptor expression may contribute to defective insulin and glucagon secretion in human type 2 diabetes. | 42 |
| 26214021 | 2015 | 5-hydroxytryptamine receptor (5-HT1DR) promotes colorectal cancer metastasis by regulating Axin1/β-catenin/MMP-7 signaling pathway. | 28 |
| 25170871 | 2014 | Down-regulation of 5-HT1B and 5-HT1D receptors inhibits proliferation, clonogenicity and invasion of human pancreatic cancer cells. | 14 |
| 25268648 | 2014 | Down-regulation of 5-HT1B and 5-HT1D receptors inhibits proliferation, clonogenicity and invasion of human pancreatic cancer cells. | 4 |
| 25170871 | 2014 | Down-regulation of 5-HT1B and 5-HT1D receptors inhibits proliferation, clonogenicity and invasion of human pancreatic cancer cells. | 14 |
| 25268648 | 2014 | Down-regulation of 5-HT1B and 5-HT1D receptors inhibits proliferation, clonogenicity and invasion of human pancreatic cancer cells. | 4 |
| 22107845 | 2012 | Chromosome 1p36 in migraine with aura: association study of the 5HT(1D) locus. | 9 |
Citation
Dessen P
HTR1D (5-hydroxytryptamine receptor 1D)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/40898/htr1d
