Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3486
MIM: 146732
HGNC: 5472
Ensembl: ENSG00000146674
Variants:
dbSNP: 3486
ClinVar: 3486
TCGA: ENSG00000146674
COSMIC: IGFBP3
RNA/Proteins
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA128406956 | fluorouracil | Chemical | ClinicalAnnotation | associated | PD | 20860465 | |
| PA445742 | Stomach Neoplasms | Disease | ClinicalAnnotation | associated | PD | 20860465 | |
| PA448871 | celecoxib | Chemical | Pathway | associated | 22336956 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38224009 | 2024 | Novel therapeutic targets, including IGFBP3, of umbilical cord mesenchymal stem-cell-conditioned medium in intrauterine adhesion. | 0 |
| 38468402 | 2024 | IGF2BP2 and IGFBP3 Genotypes, Haplotypes, and Genetic Models Studies in Polycystic Ovary Syndrome. | 0 |
| 38224009 | 2024 | Novel therapeutic targets, including IGFBP3, of umbilical cord mesenchymal stem-cell-conditioned medium in intrauterine adhesion. | 0 |
| 38468402 | 2024 | IGF2BP2 and IGFBP3 Genotypes, Haplotypes, and Genetic Models Studies in Polycystic Ovary Syndrome. | 0 |
| 36657656 | 2023 | IGFBP3 epigenetic promotion induced by METTL3 boosts cardiac fibroblast activation and fibrosis. | 4 |
| 36766747 | 2023 | Phosphorylation of IGFBP-3 by Casein Kinase 2 Blocks Its Interaction with Hyaluronan, Enabling HA-CD44 Signaling Leading to Increased NSCLC Cell Survival and Cisplatin Resistance. | 5 |
| 36800719 | 2023 | Etiological study of short stature in children and role of insulin like growth factor-1 and insulin like growth factor binding protein-3 as screening markers for growth hormone deficiency. | 1 |
| 36853324 | 2023 | The Association Between the Serum Level of IGF-1 and IGFBP-3 and the Risk of Breast Cancer among Women in the Gaza Strip. | 1 |
| 37188982 | 2023 | MicroRNA-210-3p Regulates Endometriotic Lesion Development by Targeting IGFBP3 in Baboons and Women with Endometriosis. | 3 |
| 37253773 | 2023 | Insulin-like growth factor binding protein-3 induces senescence by inhibiting telomerase activity in MCF-7 breast cancer cells. | 1 |
| 37451139 | 2023 | GATA4 inhibits odontoblastic differentiation of dental pulp stem cells through targeting IGFBP3. | 0 |
| 37511378 | 2023 | Obese Asthma Phenotype Is Associated with hsa-miR-26a-1-3p and hsa-miR-376a-3p Modulating the IGF Axis. | 0 |
| 37690686 | 2023 | Insulin-like growth factor binding protein-3 mediates hyperosmolar stress-induced mitophagy through the mechanistic target of rapamycin. | 1 |
| 37792867 | 2023 | The relationship between serum leptin, insulin-like growth factor-1, and insulin-like growth factor binding protein-3 levels and clinical parameters in primary fibromyalgia patients. | 1 |
| 37948568 | 2023 | Insulin-like growth factor binding protein 3 promoter variant (rs2854744) is associated with nonalcoholic fatty liver disease. | 2 |
Citation
Dessen P
IGFBP3 (insulin like growth factor binding protein 3)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/40932/igfbp3
