Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3586
MIM: 124092
HGNC: 5962
Ensembl: ENSG00000136634
Variants:
dbSNP: 3586
ClinVar: 3586
TCGA: ENSG00000136634
COSMIC: IL10
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA134850491 | Transplantation | Disease | ClinicalAnnotation | associated | PK | ||
| PA164712462 | Antiinflammatory agents, non-steroids | Chemical | ClinicalAnnotation | associated | PD | 28750137 | |
| PA165817016 | Kidney Transplantation | Disease | ClinicalAnnotation | associated | PK | PD | 18444945, 22094953 |
| PA447230 | HIV Infections | Disease | ClinicalAnnotation | associated | PD | 24819158 | |
| PA447247 | liver transplantation | Disease | ClinicalAnnotation | associated | PD | 21359536 | |
| PA449167 | cyclosporine | Chemical | ClinicalAnnotation | associated | PD | 18444945 | |
| PA449441 | efavirenz | Chemical | ClinicalAnnotation, Literature, MultilinkAnnotation | associated | PD | 24819158 | |
| PA450566 | mycophenolate mofetil | Chemical | ClinicalAnnotation | associated | PD | 18444945 | |
| PA451261 | rituximab | Chemical | MultilinkAnnotation | associated | 26384320 | ||
| PA451365 | sirolimus | Chemical | ClinicalAnnotation | associated | PK | 22094953 | |
| PA451578 | tacrolimus | Chemical | ClinicalAnnotation | associated | PK | PD | 21359536 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37094795 | 2024 | Interleukin 10, but not tumor necrosis factor-alpha, gene variations are associated with factor VII inhibitor development. | 0 |
| 37842994 | 2024 | IL-6, IL-10 and TNF-α gene polymorphisms in preeclampsia: a case-control study in a Mexican population. | 0 |
| 37923001 | 2024 | The association of cytokines genes (IL-6 and IL-10) with the susceptibility to schizophrenia: A systematic review and meta-analysis. | 1 |
| 37951418 | 2024 | Interleukin 10 (IL10) promoter region polymorphism is associated with IL10 serum concentrations and processing speed in healthy community-dwelling older adults. | 0 |
| 37953401 | 2024 | Association of IL-23R and IL-10 variations with Behçet disease: a genetic analysis study. | 0 |
| 37955408 | 2024 | Interleukin-10 promoter polymorphisms and haplotypes in patients with Guillain-Barré syndrome. | 0 |
| 38169599 | 2024 | Initial IL-10 production dominates the therapy of mesenchymal stem cell scaffold in spinal cord injury. | 1 |
| 38263289 | 2024 | An IL-10/DEL-1 axis supports granulopoiesis and survival from sepsis in early life. | 0 |
| 38279997 | 2024 | The complex role of IL-10 in malignant ascites: a review. | 0 |
| 38285796 | 2024 | Correlation between rs1800871, rs1800872 and rs1800896 Polymorphisms at IL-10 Gene and Lung Cancer Risk. | 1 |
| 38286270 | 2024 | Cytokines signatures and susceptibility to cutaneous leishmaniasis in patients from Sistan and Baluchestan province of Iran. | 0 |
| 38287362 | 2024 | Association of IL-10-592 C > A /-1082 A > G and the TNFα -308 G > A with susceptibility to COVID-19 and clinical outcomes. | 1 |
| 38365575 | 2024 | The pertinence of gastric cancer and interleukin 10-819 single nucleotide polymorphisms: a meta-analysis and systematic review. | 0 |
| 38400050 | 2024 | Inflammatory Polymorphisms (IL-6 rs1800796, IL-10 rs1800896, TNF-α rs1800629, and IFITM3 rs12252) Are Not Associated with Post-COVID Symptoms in Previously Hospitalized COVID-19 Survivors. | 0 |
| 38415531 | 2024 | Interleukin-6 And Interleukin-10 Polymorphisms In Chronic Lymphoid Leukemia Patients. | 0 |
Citation
Dessen P
IL10 (interleukin 10)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/40939/il10
