Identity
HGNC
LOCATION
19p13.11
LOCUSID
ALIAS
INO1,INOS,IPS,IPS
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51477
MIM: 611670
HGNC: 29821
Ensembl: ENSG00000105655
Variants:
dbSNP: 51477
ClinVar: 51477
TCGA: ENSG00000105655
COSMIC: ISYNA1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36871899 | 2023 | Cigarette smoke induces the ROS accumulation and iNOS activation through deactivation of Nrf-2/SIRT3 axis to mediate the human bronchial epithelium ferroptosis. | 9 |
| 37105506 | 2023 | The myo-inositol biosynthesis rate-limiting enzyme ISYNA1 suppresses the stemness of ovarian cancer via Notch1 pathway. | 2 |
| 36871899 | 2023 | Cigarette smoke induces the ROS accumulation and iNOS activation through deactivation of Nrf-2/SIRT3 axis to mediate the human bronchial epithelium ferroptosis. | 9 |
| 37105506 | 2023 | The myo-inositol biosynthesis rate-limiting enzyme ISYNA1 suppresses the stemness of ovarian cancer via Notch1 pathway. | 2 |
| 32779876 | 2020 | Musashi2 promotes the progression of pancreatic cancer through a novel ISYNA1-p21/ZEB-1 pathway. | 14 |
| 32779876 | 2020 | Musashi2 promotes the progression of pancreatic cancer through a novel ISYNA1-p21/ZEB-1 pathway. | 14 |
| 30861650 | 2019 | [Clinicopathological significance of ISYNA1 expression in pancreatic ductal adenocarcinoma]. | 0 |
| 31495492 | 2019 | ISYNA1 is overexpressed in bladder carcinoma and regulates cell proliferation and apoptosis. | 6 |
| 30861650 | 2019 | [Clinicopathological significance of ISYNA1 expression in pancreatic ductal adenocarcinoma]. | 0 |
| 31495492 | 2019 | ISYNA1 is overexpressed in bladder carcinoma and regulates cell proliferation and apoptosis. | 6 |
| 23902760 | 2013 | Phosphorylation regulates myo-inositol-3-phosphate synthase: a novel regulatory mechanism of inositol biosynthesis. | 26 |
| 23902760 | 2013 | Phosphorylation regulates myo-inositol-3-phosphate synthase: a novel regulatory mechanism of inositol biosynthesis. | 26 |
| 22707096 | 2012 | L-myo-inositol-1-phosphate synthase expressed in developing organ: isolation and characterisation of the enzyme from human fetal liver. | 1 |
| 22707096 | 2012 | L-myo-inositol-1-phosphate synthase expressed in developing organ: isolation and characterisation of the enzyme from human fetal liver. | 1 |
| 15464731 | 2004 | E2F1 regulation of the human myo-inositol 1-phosphate synthase (ISYNA1) gene promoter. | 6 |
Citation
Dessen P
ISYNA1 (inositol-3-phosphate synthase 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-12-01
Online version: http://atlasgeneticsoncology.org/gene/40998/isyna1
