Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3676
MIM: 192975
HGNC: 6140
Ensembl: ENSG00000115232
Variants:
dbSNP: 3676
ClinVar: 3676
TCGA: ENSG00000115232
COSMIC: ITGA4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000115232 | ENST00000233573 | E7EP60 |
| ENSG00000115232 | ENST00000339307 | P13612 |
| ENSG00000115232 | ENST00000397033 | P13612 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38154529 | 2024 | Cancer-Associated Fibroblast Induces Acinar-to-Ductal Cell Transdifferentiation and Pancreatic Cancer Initiation Via LAMA5/ITGA4 Axis. | 3 |
| 38311553 | 2024 | [Association of ITGA4 and ICAM-1 gene polymorphisms with the risk and clinicopathological characteristics of Crohn's disease]. | 0 |
| 38154529 | 2024 | Cancer-Associated Fibroblast Induces Acinar-to-Ductal Cell Transdifferentiation and Pancreatic Cancer Initiation Via LAMA5/ITGA4 Axis. | 3 |
| 38311553 | 2024 | [Association of ITGA4 and ICAM-1 gene polymorphisms with the risk and clinicopathological characteristics of Crohn's disease]. | 0 |
| 37330909 | 2023 | LRP12 is an endogenous transmembrane inactivator of α4 integrins. | 2 |
| 37330909 | 2023 | LRP12 is an endogenous transmembrane inactivator of α4 integrins. | 2 |
| 33724131 | 2022 | Increased Levels of VCAM-1 in Sera and VLA-4 Expression on Neutrophils in Dermatomyositis with Interstitial Lung Disease. | 1 |
| 34783040 | 2022 | Elastin MIcrofibriL INterfacer1 (EMILIN-1) is an alternative prosurvival VLA-4 ligand in chronic lymphocytic leukemia. | 2 |
| 35776688 | 2022 | Low CD49d expression in newly diagnosed chronic lymphocytic leukaemia may be associated with high-risk features and reduced treatment-free-intervals. | 1 |
| 35968588 | 2022 | [The correlation of CD49d expression pattern with molecular genetics and hotspot gene mutants in patients with chronic lymphocytic leukemia]. | 0 |
| 33724131 | 2022 | Increased Levels of VCAM-1 in Sera and VLA-4 Expression on Neutrophils in Dermatomyositis with Interstitial Lung Disease. | 1 |
| 34783040 | 2022 | Elastin MIcrofibriL INterfacer1 (EMILIN-1) is an alternative prosurvival VLA-4 ligand in chronic lymphocytic leukemia. | 2 |
| 35776688 | 2022 | Low CD49d expression in newly diagnosed chronic lymphocytic leukaemia may be associated with high-risk features and reduced treatment-free-intervals. | 1 |
| 35968588 | 2022 | [The correlation of CD49d expression pattern with molecular genetics and hotspot gene mutants in patients with chronic lymphocytic leukemia]. | 0 |
| 32616529 | 2021 | CD44 engagement enhances acute myeloid leukemia cell adhesion to the bone marrow microenvironment by increasing VLA-4 avidity. | 12 |
Citation
Dessen P
ITGA4 (integrin subunit alpha 4)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/41005/itga4
