Identity
HGNC
LOCATION
2q32.1
LOCUSID
ALIAS
CD51,MSK8,VNRA,VTNR
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3685
MIM: 193210
HGNC: 6150
Ensembl: ENSG00000138448
Variants:
dbSNP: 3685
ClinVar: 3685
TCGA: ENSG00000138448
COSMIC: ITGAV
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37884208 | 2024 | Integrin αvβ1 facilitates ACE2-mediated entry of SARS-CoV-2. | 0 |
| 38123132 | 2024 | Matrix metalloproteinase-2 inducing COL1A1 synthesis via integrin alpha Ⅴ promotes invasion and metastasis of cholangiocarcinoma cells. | 1 |
| 38395907 | 2024 | Novel prognostic marker TGFBI affects the migration and invasion function of ovarian cancer cells and activates the integrin αvβ3-PI3K-Akt signaling pathway. | 0 |
| 38532364 | 2024 | A decrease in integrin α5β1/FAK is associated with increased apoptosis of aortic smooth muscle cells in acute type a aortic dissection. | 0 |
| 38588407 | 2024 | Integrin αvβ3 Upregulation in Response to Nutrient Stress Promotes Lung Cancer Cell Metabolic Plasticity. | 1 |
| 37884208 | 2024 | Integrin αvβ1 facilitates ACE2-mediated entry of SARS-CoV-2. | 0 |
| 38123132 | 2024 | Matrix metalloproteinase-2 inducing COL1A1 synthesis via integrin alpha Ⅴ promotes invasion and metastasis of cholangiocarcinoma cells. | 1 |
| 38395907 | 2024 | Novel prognostic marker TGFBI affects the migration and invasion function of ovarian cancer cells and activates the integrin αvβ3-PI3K-Akt signaling pathway. | 0 |
| 38532364 | 2024 | A decrease in integrin α5β1/FAK is associated with increased apoptosis of aortic smooth muscle cells in acute type a aortic dissection. | 0 |
| 38588407 | 2024 | Integrin αvβ3 Upregulation in Response to Nutrient Stress Promotes Lung Cancer Cell Metabolic Plasticity. | 1 |
| 37280310 | 2023 | Molecular basis for the recognition of 24-(S)-hydroxycholesterol by integrin αvβ3. | 2 |
| 37604269 | 2023 | Combined inhibition of surface CD51 and γ-secretase-mediated CD51 cleavage improves therapeutic efficacy in experimental metastatic hepatocellular carcinoma. | 3 |
| 37904190 | 2023 | Regulation of the integrin αVβ3- actin filaments axis in early osteogenic differentiation of human mesenchymal stem cells under cyclic tensile stress. | 1 |
| 37909974 | 2023 | Interaction of Integrin αvβ8 With Type I Collagen Promotes Squamous Cell Carcinoma Cell Motility via RAC1 Activation. | 0 |
| 38009896 | 2023 | Integrin-αvβ3 is a Therapeutically Targetable Fundamental Factor in Medulloblastoma Tumorigenicity and Radioresistance. | 0 |
Citation
Dessen P
ITGAV (integrin subunit alpha V)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/41015/itgav
