Identity
HGNC
LOCATION
21q22.3
LOCUSID
ALIAS
CD18,LAD,LCAMB,LFA-1,MAC-1,MF17,MFI7
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3689
MIM: 600065
HGNC: 6155
Ensembl: ENSG00000160255
Variants:
dbSNP: 3689
ClinVar: 3689
TCGA: ENSG00000160255
COSMIC: ITGB2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37923103 | 2024 | Identification of an association between coronary heart disease and ITGB2 methylation in peripheral blood by a case-control study. | 1 |
| 37937521 | 2024 | Decreased toll-like receptor 4 and CD11b/CD18 expression on peripheral monocytes of hypertensive patients correlates with a lesser extent of endothelial damage: a preliminary study. | 0 |
| 38150154 | 2024 | ITGB2-ICAM1 axis promotes liver metastasis in BAP1-mutated uveal melanoma with retained hypoxia and ECM signatures. | 3 |
| 37923103 | 2024 | Identification of an association between coronary heart disease and ITGB2 methylation in peripheral blood by a case-control study. | 1 |
| 37937521 | 2024 | Decreased toll-like receptor 4 and CD11b/CD18 expression on peripheral monocytes of hypertensive patients correlates with a lesser extent of endothelial damage: a preliminary study. | 0 |
| 38150154 | 2024 | ITGB2-ICAM1 axis promotes liver metastasis in BAP1-mutated uveal melanoma with retained hypoxia and ECM signatures. | 3 |
| 37250717 | 2023 | Identifying C1QB, ITGAM, and ITGB2 as potential diagnostic candidate genes for diabetic nephropathy using bioinformatics analysis. | 3 |
| 37371473 | 2023 | Targeting Neutrophil β(2)-Integrins: A Review of Relevant Resources, Tools, and Methods. | 5 |
| 37644537 | 2023 | Association of integrin-β2 polymorphism and expression with the risk of rheumatoid arthritis and osteoarthritis in Egyptian patients. | 0 |
| 37660569 | 2023 | Characterization of tumor microenvironment in glioblastoma multiforme identifies ITGB2 as a key immune and stromal related regulator in glial cell types. | 3 |
| 37892170 | 2023 | Aminopeptidase N/CD13 Crosslinking Promotes the Activation and Membrane Expression of Integrin CD11b/CD18. | 0 |
| 37250717 | 2023 | Identifying C1QB, ITGAM, and ITGB2 as potential diagnostic candidate genes for diabetic nephropathy using bioinformatics analysis. | 3 |
| 37371473 | 2023 | Targeting Neutrophil β(2)-Integrins: A Review of Relevant Resources, Tools, and Methods. | 5 |
| 37644537 | 2023 | Association of integrin-β2 polymorphism and expression with the risk of rheumatoid arthritis and osteoarthritis in Egyptian patients. | 0 |
| 37660569 | 2023 | Characterization of tumor microenvironment in glioblastoma multiforme identifies ITGB2 as a key immune and stromal related regulator in glial cell types. | 3 |
Citation
Dessen P
ITGB2 (integrin subunit beta 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/41018/itgb2
