Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54455
MIM: 609109
HGNC: 29249
Ensembl: ENSG00000037637
Variants:
dbSNP: 54455
ClinVar: 54455
TCGA: ENSG00000037637
COSMIC: FBXO42
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000037637 | ENST00000375592 | Q6P3S6 |
| ENSG00000037637 | ENST00000375592 | A0A024QZB0 |
| ENSG00000037637 | ENST00000444116 | X6RKU3 |
| ENSG00000037637 | ENST00000456164 | X6RKU3 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31549767 | 2020 | A genome-wide CRISPR screen identifies FBXO42 involvement in resistance toward MEK inhibition in NRAS-mutant melanoma. | 11 |
| 31549767 | 2020 | A genome-wide CRISPR screen identifies FBXO42 involvement in resistance toward MEK inhibition in NRAS-mutant melanoma. | 11 |
| 25792601 | 2015 | SCF(JFK) is a bona fide E3 ligase for ING4 and a potent promoter of the angiogenesis and metastasis of breast cancer. | 27 |
| 25792601 | 2015 | SCF(JFK) is a bona fide E3 ligase for ING4 and a potent promoter of the angiogenesis and metastasis of breast cancer. | 27 |
| 24063688 | 2013 | Genetic analysis of the FBXO42 gene in Chinese Han patients with Parkinson's disease. | 1 |
| 24063688 | 2013 | Genetic analysis of the FBXO42 gene in Chinese Han patients with Parkinson's disease. | 1 |
| 21127074 | 2011 | Substrate phosphorylation and feedback regulation in JFK-promoted p53 destabilization. | 14 |
| 21127074 | 2011 | Substrate phosphorylation and feedback regulation in JFK-promoted p53 destabilization. | 14 |
| 19509332 | 2009 | JFK, a Kelch domain-containing F-box protein, links the SCF complex to p53 regulation. | 48 |
| 19509332 | 2009 | JFK, a Kelch domain-containing F-box protein, links the SCF complex to p53 regulation. | 48 |
Citation
Dessen P
FBXO42 (F-box protein 42)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/41064/fbxo42
