Identity
HGNC
LOCATION
17q24.2
LOCUSID
ALIAS
IPOA1,QIP2,RCH1,SRP1-alpha,SRP1alpha
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3838
MIM: 600685
HGNC: 6395
Ensembl: ENSG00000182481
Variants:
dbSNP: 3838
ClinVar: 3838
TCGA: ENSG00000182481
COSMIC: KPNA2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36799424 | 2024 | Hsa_Circ_0000021 Sponges miR-3940-3p/KPNA2 Expression to Promote Cervical Cancer Progression. | 1 |
| 38225348 | 2024 | Analysis of the effects of importin α1 on the nuclear translocation of IL-1α in HeLa cells. | 0 |
| 36799424 | 2024 | Hsa_Circ_0000021 Sponges miR-3940-3p/KPNA2 Expression to Promote Cervical Cancer Progression. | 1 |
| 38225348 | 2024 | Analysis of the effects of importin α1 on the nuclear translocation of IL-1α in HeLa cells. | 0 |
| 36539367 | 2023 | Long noncoding RNA TUG1 decreases bladder cancer chemo-sensitivity toward doxorubicin through elevating KPNA2 expression and activating the PI3K/AKT pathway via adsorbing miR-582-5p. | 2 |
| 36583484 | 2023 | MiR-101-3p targets KPNA2 to inhibit the progression of lung squamous cell carcinoma cell lines. | 2 |
| 37121148 | 2023 | Novel roles of karyopherin subunit alpha 2 in hepatocellular carcinoma. | 1 |
| 37423952 | 2023 | ZNF143 facilitates the growth and migration of glioma cells by regulating KPNA2-mediated Hippo signalling. | 1 |
| 38283360 | 2023 | Mutational analysis of SARS-CoV-2 ORF6-KPNA2 binding interface and identification of potent small molecule inhibitors to recuse the host immune system. | 0 |
| 36539367 | 2023 | Long noncoding RNA TUG1 decreases bladder cancer chemo-sensitivity toward doxorubicin through elevating KPNA2 expression and activating the PI3K/AKT pathway via adsorbing miR-582-5p. | 2 |
| 36583484 | 2023 | MiR-101-3p targets KPNA2 to inhibit the progression of lung squamous cell carcinoma cell lines. | 2 |
| 37121148 | 2023 | Novel roles of karyopherin subunit alpha 2 in hepatocellular carcinoma. | 1 |
| 37423952 | 2023 | ZNF143 facilitates the growth and migration of glioma cells by regulating KPNA2-mediated Hippo signalling. | 1 |
| 38283360 | 2023 | Mutational analysis of SARS-CoV-2 ORF6-KPNA2 binding interface and identification of potent small molecule inhibitors to recuse the host immune system. | 0 |
| 34773335 | 2022 | Nuclear accumulation of KPNA2 impacts radioresistance through positive regulation of the PLSCR1-STAT1 loop in lung adenocarcinoma. | 7 |
Citation
Dessen P
KPNA2 (karyopherin subunit alpha 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/41097/kpna2
