KTN1 (kinectin 1)

2003-02-01  

Identity

HGNC
LOCATION
14q22.3
LOCUSID
ALIAS
CG1,KNT,MU-RMS-40.19
FUSION GENES

Other Information

Locus ID:

NCBI: 3895
MIM: 600381
HGNC: 6467
Ensembl: ENSG00000126777

Variants:

dbSNP: 3895
ClinVar: 3895
TCGA: ENSG00000126777
COSMIC: KTN1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000126777ENST00000395308Q86UP2
ENSG00000126777ENST00000395309Q86UP2
ENSG00000126777ENST00000395311Q86UP2
ENSG00000126777ENST00000395314Q86UP2
ENSG00000126777ENST00000395314A0A024R663
ENSG00000126777ENST00000413890Q86UP2
ENSG00000126777ENST00000438792Q86UP2
ENSG00000126777ENST00000459737Q86UP2
ENSG00000126777ENST00000459737A0A024R663
ENSG00000126777ENST00000553360H0YJZ8
ENSG00000126777ENST00000553624G3V5P0
ENSG00000126777ENST00000553710H0YJB7
ENSG00000126777ENST00000554294H0YJP2
ENSG00000126777ENST00000554507G3V4Y7
ENSG00000126777ENST00000554567G3V5Q0
ENSG00000126777ENST00000554570H0YJV5
ENSG00000126777ENST00000554890G3V5G2
ENSG00000126777ENST00000555498G3V4L8
ENSG00000126777ENST00000555573B7Z6P3
ENSG00000126777ENST00000557267G3V475

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
RHO GTPase EffectorsREACTOMER-HSA-195258
RHO GTPases activate KTN1REACTOMER-HSA-5625970

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
379925462024A genetic and transcriptomic assessment of the KTN1 gene in Parkinson's disease risk.0
384483402024KTN1 mediated unfolded protein response protects keratinocytes from ionizing radiation-induced DNA damage.0
379925462024A genetic and transcriptomic assessment of the KTN1 gene in Parkinson's disease risk.0
384483402024KTN1 mediated unfolded protein response protects keratinocytes from ionizing radiation-induced DNA damage.0
321158112021Significant, replicable, and functional associations between KTN1 variants and alcohol and drug codependence.5
342191292021Kinectin 1 promotes the growth of triple-negative breast cancer via directly co-activating NF-kappaB/p65 and enhancing its transcriptional activity.5
345913542021Human microRNA-182-5p and kinectin 1: Potential biomarkers for prognosis in oral squamous cell carcinoma.0
321158112021Significant, replicable, and functional associations between KTN1 variants and alcohol and drug codependence.5
342191292021Kinectin 1 promotes the growth of triple-negative breast cancer via directly co-activating NF-kappaB/p65 and enhancing its transcriptional activity.5
345913542021Human microRNA-182-5p and kinectin 1: Potential biomarkers for prognosis in oral squamous cell carcinoma.0
321909802020KTN1 variants and risk for attention deficit hyperactivity disorder.9
325259922020Rab18 regulates focal adhesion dynamics by interacting with kinectin-1 at the endoplasmic reticulum.9
329567412020Associations of attention distractibility with attention deficit and with variation in the KTN1 gene.2
321909802020KTN1 variants and risk for attention deficit hyperactivity disorder.9
325259922020Rab18 regulates focal adhesion dynamics by interacting with kinectin-1 at the endoplasmic reticulum.9

Citation

Dessen P

KTN1 (kinectin 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41108/js/css/favicon/favicon-16x16.png