Identity
HGNC
LOCATION
11q12.1
LOCUSID
ALIAS
DT2P1G7,LCMR1,MED19AS
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 219541
MIM: 612385
HGNC: 29600
Ensembl: ENSG00000156603
Variants:
dbSNP: 219541
ClinVar: 219541
TCGA: ENSG00000156603
COSMIC: MED19
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000156603 | ENST00000337672 | A0JLT2 |
| ENSG00000156603 | ENST00000431606 | J3KR33 |
| ENSG00000156603 | ENST00000645681 | A0JLT2 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA443309 | Alcoholism | Disease | ClinicalAnnotation | associated | PD | 32451486 | |
| PA448073 | ethanol | Chemical | ClinicalAnnotation | associated | PD | 32451486 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37880276 | 2023 | MED19 encodes two unique protein isoforms that confer prostate cancer growth under low androgen through distinct gene expression programs. | 0 |
| 37880276 | 2023 | MED19 encodes two unique protein isoforms that confer prostate cancer growth under low androgen through distinct gene expression programs. | 0 |
| 35184651 | 2022 | Lung cancer metastasis-related protein 1 promotes the transferring from advanced metastatic prostate cancer to castration-resistant prostate cancer by activating the glucocorticoid receptor α signal pathway. | 4 |
| 35184651 | 2022 | Lung cancer metastasis-related protein 1 promotes the transferring from advanced metastatic prostate cancer to castration-resistant prostate cancer by activating the glucocorticoid receptor α signal pathway. | 4 |
| 33513133 | 2021 | MED19 alters AR occupancy and gene expression in prostate cancer cells, driving MAOA expression and growth under low androgen. | 7 |
| 34038190 | 2021 | The role of mediator complex subunit 19 in human diseases. | 2 |
| 33513133 | 2021 | MED19 alters AR occupancy and gene expression in prostate cancer cells, driving MAOA expression and growth under low androgen. | 7 |
| 34038190 | 2021 | The role of mediator complex subunit 19 in human diseases. | 2 |
| 30161287 | 2019 | Med19 is involved in chemoresistance by mediating autophagy through HMGB1 in breast cancer. | 14 |
| 30583076 | 2019 | Med19 is targeted by miR-101-3p/miR-422a and promotes breast cancer progression by regulating the EGFR/MEK/ERK signaling pathway. | 20 |
| 31715665 | 2019 | [Knockdown of mediator complex subunit 19 suppresses the migration and invasion and epithelial-mesenchymal transition in prostate cancer PC3 cells]. | 0 |
| 30161287 | 2019 | Med19 is involved in chemoresistance by mediating autophagy through HMGB1 in breast cancer. | 14 |
| 30583076 | 2019 | Med19 is targeted by miR-101-3p/miR-422a and promotes breast cancer progression by regulating the EGFR/MEK/ERK signaling pathway. | 20 |
| 31715665 | 2019 | [Knockdown of mediator complex subunit 19 suppresses the migration and invasion and epithelial-mesenchymal transition in prostate cancer PC3 cells]. | 0 |
| 27375018 | 2017 | A large-scale RNAi screen identifies LCMR1 as a critical regulator of Tspan8-mediated melanoma invasion. | 11 |
Citation
Dessen P
MED19 (mediator complex subunit 19)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/41131/med19
