Identity
HGNC
LOCATION
1q42.12
LOCUSID
ALIAS
LEFTB,LEFTYB
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10637
MIM: 603037
HGNC: 6552
Ensembl: ENSG00000243709
Variants:
dbSNP: 10637
ClinVar: 10637
TCGA: ENSG00000243709
COSMIC: LEFTY1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000243709 | ENST00000272134 | O75610 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37097539 | 2023 | Association of maternal hypertension and diabetes with variants of the NKX2-5, LEFTY1 and LEFTY2 genes in children with congenital heart defects: a case-control study from Pakistani Population. | 1 |
| 37097539 | 2023 | Association of maternal hypertension and diabetes with variants of the NKX2-5, LEFTY1 and LEFTY2 genes in children with congenital heart defects: a case-control study from Pakistani Population. | 1 |
| 34680872 | 2021 | Expression of Cytokine-Coding Genes BMP8B, LEFTY1 and INSL5 Could Distinguish between Ulcerative Colitis and Crohn's Disease. | 2 |
| 34680872 | 2021 | Expression of Cytokine-Coding Genes BMP8B, LEFTY1 and INSL5 Could Distinguish between Ulcerative Colitis and Crohn's Disease. | 2 |
| 32022949 | 2020 | Expression of Lefty predicts Merkel cell carcinoma-specific death. | 0 |
| 33111989 | 2020 | Requirements of LEFTY and Nodal overexpression for tumor cell survival under hypoxia in glioblastoma. | 4 |
| 32022949 | 2020 | Expression of Lefty predicts Merkel cell carcinoma-specific death. | 0 |
| 33111989 | 2020 | Requirements of LEFTY and Nodal overexpression for tumor cell survival under hypoxia in glioblastoma. | 4 |
| 29268772 | 2017 | A functional role of LEFTY during progesterone therapy for endometrial carcinoma. | 2 |
| 30027725 | 2017 | Low Expression of LEFTY1 in Placental Villi Is Associated with Early Unexplained Miscarriage. | 1 |
| 29268772 | 2017 | A functional role of LEFTY during progesterone therapy for endometrial carcinoma. | 2 |
| 30027725 | 2017 | Low Expression of LEFTY1 in Placental Villi Is Associated with Early Unexplained Miscarriage. | 1 |
| 25339094 | 2014 | Lefty inhibits in vitro decidualization by regulating P57 and cyclin D1 expressions. | 6 |
| 25339094 | 2014 | Lefty inhibits in vitro decidualization by regulating P57 and cyclin D1 expressions. | 6 |
| 23407711 | 2013 | Suppression of Lefty expression in induced pluripotent cancer cells. | 9 |
Citation
Dessen P
LEFTY1 (left-right determination factor 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-12-01
Online version: http://atlasgeneticsoncology.org/gene/41138/lefty1
