Identity
HGNC
LOCATION
17q21.2
LOCUSID
ALIAS
D11LGP2,D11lgp2e,LGP2,RLR-3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79132
MIM: 608588
HGNC: 29517
Ensembl: ENSG00000108771
Variants:
dbSNP: 79132
ClinVar: 79132
TCGA: ENSG00000108771
COSMIC: DHX58
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38015453 | 2024 | Unraveling blunt-end RNA binding and ATPase-driven translocation activities of the RIG-I family helicase LGP2. | 1 |
| 38309507 | 2024 | Contrasting functions of ATP hydrolysis by MDA5 and LGP2 in viral RNA sensing. | 2 |
| 38015453 | 2024 | Unraveling blunt-end RNA binding and ATPase-driven translocation activities of the RIG-I family helicase LGP2. | 1 |
| 38309507 | 2024 | Contrasting functions of ATP hydrolysis by MDA5 and LGP2 in viral RNA sensing. | 2 |
| 36152765 | 2023 | Effect of variants in LGP2 on MDA5-mediated activation of interferon response and suppression of hepatitis D virus replication. | 4 |
| 36515138 | 2023 | K63-linked polyubiquitination of LGP2 by Riplet regulates RIG-I-dependent innate immune response. | 1 |
| 36743960 | 2023 | Genetic variants of IFIH1 and DHX58 affect the chronicity of hepatitis C in the Chinese Han population. | 0 |
| 37336810 | 2023 | The RNA-Binding Proteins OAS1, ZFP36L2, and DHX58 Are Involved in the Regulation of CD44 mRNA Splicing in Colorectal Cancer Cells. | 1 |
| 36152765 | 2023 | Effect of variants in LGP2 on MDA5-mediated activation of interferon response and suppression of hepatitis D virus replication. | 4 |
| 36515138 | 2023 | K63-linked polyubiquitination of LGP2 by Riplet regulates RIG-I-dependent innate immune response. | 1 |
| 36743960 | 2023 | Genetic variants of IFIH1 and DHX58 affect the chronicity of hepatitis C in the Chinese Han population. | 0 |
| 37336810 | 2023 | The RNA-Binding Proteins OAS1, ZFP36L2, and DHX58 Are Involved in the Regulation of CD44 mRNA Splicing in Colorectal Cancer Cells. | 1 |
| 35156720 | 2022 | RNA sensing via the RIG-I-like receptor LGP2 is essential for the induction of a type I IFN response in ADAR1 deficiency. | 16 |
| 36059486 | 2022 | Function conservation and disparities of zebrafish and human LGP2 genes in fish and mammalian cells responsive to poly(I:C). | 4 |
| 35156720 | 2022 | RNA sensing via the RIG-I-like receptor LGP2 is essential for the induction of a type I IFN response in ADAR1 deficiency. | 16 |
Citation
Dessen P
DHX58 (DExH-box helicase 58)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41150/dhx58
