LMCD1 (LIM and cysteine rich domains 1)

2003-02-01  

Identity

HGNC
LOCATION
3p25.3
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 29995
MIM: 604859
HGNC: 6633
Ensembl: ENSG00000071282

Variants:

dbSNP: 29995
ClinVar: 29995
TCGA: ENSG00000071282
COSMIC: LMCD1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000071282ENST00000157600Q9NZU5
ENSG00000071282ENST00000397386B4DEY6
ENSG00000071282ENST00000415597C9IYS1
ENSG00000071282ENST00000426878H7C3D2
ENSG00000071282ENST00000454244Q9NZU5
ENSG00000071282ENST00000456506F8WB09

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Surfactant metabolismREACTOMER-HSA-5683826

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
361033782023Critical Role of LMCD1 in Promoting Profibrotic Characteristics of Lung Myofibroblasts in Experimental and Scleroderma-Associated Lung Fibrosis.5
370391512023LIM and Cysteine-Rich Domains 1 Promotes Transforming Growth Factor β1-Induced Epithelial-Mesenchymal Transition in Human Kidney 2 Cells.1
361033782023Critical Role of LMCD1 in Promoting Profibrotic Characteristics of Lung Myofibroblasts in Experimental and Scleroderma-Associated Lung Fibrosis.5
370391512023LIM and Cysteine-Rich Domains 1 Promotes Transforming Growth Factor β1-Induced Epithelial-Mesenchymal Transition in Human Kidney 2 Cells.1
358427722022LMCD1 facilitates the induction of pluripotency via cell proliferation, metabolism, and epithelial-mesenchymal transition.0
358427722022LMCD1 facilitates the induction of pluripotency via cell proliferation, metabolism, and epithelial-mesenchymal transition.0
321607732020Myristoylation of LMCD1 Leads to Its Species-Specific Derepression of E2F1 and NFATc1 in the Modulation of CDC6 and IL-33 Expression During Development of Vascular Lesions.10
321607732020Myristoylation of LMCD1 Leads to Its Species-Specific Derepression of E2F1 and NFATc1 in the Modulation of CDC6 and IL-33 Expression During Development of Vascular Lesions.10
315014112019LMCD1 promotes osteogenic differentiation of human bone marrow stem cells by regulating BMP signaling.8
316661222019LIM and cysteine-rich domains 1 (LMCD1) regulates skeletal muscle hypertrophy, calcium handling, and force.10
315014112019LMCD1 promotes osteogenic differentiation of human bone marrow stem cells by regulating BMP signaling.8
316661222019LIM and cysteine-rich domains 1 (LMCD1) regulates skeletal muscle hypertrophy, calcium handling, and force.10
293261632018LIM and cysteine-rich domains 1 is required for thrombin-induced smooth muscle cell proliferation and promotes atherogenesis.12
293261632018LIM and cysteine-rich domains 1 is required for thrombin-induced smooth muscle cell proliferation and promotes atherogenesis.12
268798862016A common variant association study reveals novel susceptibility loci for low HDL-cholesterol levels in ethnic Arabs.13

Citation

Dessen P

LMCD1 (LIM and cysteine rich domains 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41165/lmcd1