Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84445
MIM: 610454
HGNC: 29381
Ensembl: ENSG00000107816
Variants:
dbSNP: 84445
ClinVar: 84445
TCGA: ENSG00000107816
COSMIC: LZTS2
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38740232 | 2024 | Phosphorylation of LZTS2 by PLK1 activates the Wnt pathway. | 0 |
| 38740232 | 2024 | Phosphorylation of LZTS2 by PLK1 activates the Wnt pathway. | 0 |
| 35287088 | 2022 | LZTS2: A novel and independent prognostic biomarker for clear cell renal cell carcinoma. | 1 |
| 35287088 | 2022 | LZTS2: A novel and independent prognostic biomarker for clear cell renal cell carcinoma. | 1 |
| 33420362 | 2021 | β-Trcp and CK1δ-mediated degradation of LZTS2 activates PI3K/AKT signaling to drive tumorigenesis and metastasis in hepatocellular carcinoma. | 12 |
| 33420362 | 2021 | β-Trcp and CK1δ-mediated degradation of LZTS2 activates PI3K/AKT signaling to drive tumorigenesis and metastasis in hepatocellular carcinoma. | 12 |
| 29409973 | 2018 | LZTS2 inhibits PI3K/AKT activation and radioresistance in nasopharyngeal carcinoma by interacting with p85. | 26 |
| 29499699 | 2018 | LZTS2 promoter hypermethylation: a potential biomarker for the diagnosis and prognosis of laryngeal squamous cell carcinoma. | 7 |
| 29409973 | 2018 | LZTS2 inhibits PI3K/AKT activation and radioresistance in nasopharyngeal carcinoma by interacting with p85. | 26 |
| 29499699 | 2018 | LZTS2 promoter hypermethylation: a potential biomarker for the diagnosis and prognosis of laryngeal squamous cell carcinoma. | 7 |
| 23275340 | 2013 | Deletion of leucine zipper tumor suppressor 2 (Lzts2) increases susceptibility to tumor development. | 15 |
| 23761130 | 2013 | Leucine zipper tumor suppressor 2 inhibits cell proliferation and regulates Lef/Tcf-dependent transcription through Akt/GSK3β signaling pathway in lung cancer. | 4 |
| 23275340 | 2013 | Deletion of leucine zipper tumor suppressor 2 (Lzts2) increases susceptibility to tumor development. | 15 |
| 23761130 | 2013 | Leucine zipper tumor suppressor 2 inhibits cell proliferation and regulates Lef/Tcf-dependent transcription through Akt/GSK3β signaling pathway in lung cancer. | 4 |
| 20508983 | 2011 | Centrosome-related genes, genetic variation, and risk of breast cancer. | 21 |
Citation
Dessen P
LZTS2 (leucine zipper tumor suppressor 2)
Atlas Genet Cytogenet Oncol Haematol. 2004-04-01
Online version: http://atlasgeneticsoncology.org/gene/41223/lzts2
