MAGEB2 (MAGE family member B2)

2003-02-01  

Identity

HGNC
MAGEB2
LOCATION
Xp21.2
LOCUSID
4113
ALIAS
CT3.2,DAM6,MAGE-XP-2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4113
MIM: 300098
HGNC: 6809
Ensembl: ENSG00000099399

Variants:

dbSNP: 4113
ClinVar: 4113
TCGA: ENSG00000099399
COSMIC: MAGEB2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000099399ENST00000378988O15479

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
356182112022Cancer germline antigen gene MAGEB2 promotes cell invasion and correlates with immune microenvironment and immunotherapeutic efficiency in laryngeal cancer.7
356182112022Cancer germline antigen gene MAGEB2 promotes cell invasion and correlates with immune microenvironment and immunotherapeutic efficiency in laryngeal cancer.7
337414332021Expression of the tumor-expressed protein MageB2 enhances rRNA transcription.2
337414332021Expression of the tumor-expressed protein MageB2 enhances rRNA transcription.2
266427942016Aberrant demethylation and expression of MAGEB2 in a subset of malignant peripheral nerve sheath tumors from neurofibromatosis type 1.3
266427942016Aberrant demethylation and expression of MAGEB2 in a subset of malignant peripheral nerve sheath tumors from neurofibromatosis type 1.3
264682942015Human MageB2 Protein Expression Enhances E2F Transcriptional Activity, Cell Proliferation, and Resistance to Ribotoxic Stress.16
264682942015Human MageB2 Protein Expression Enhances E2F Transcriptional Activity, Cell Proliferation, and Resistance to Ribotoxic Stress.16
230290772012MAGEB2 is activated by promoter demethylation in head and neck squamous cell carcinoma.16
230290772012MAGEB2 is activated by promoter demethylation in head and neck squamous cell carcinoma.16
170122252007Valproate induces widespread epigenetic reprogramming which involves demethylation of specific genes.74
170122252007Valproate induces widespread epigenetic reprogramming which involves demethylation of specific genes.74
120188522002Hypertonicity induction of melanoma antigen, a tumor-associated antigen.3
120188522002Hypertonicity induction of melanoma antigen, a tumor-associated antigen.3

Citation

Dessen P

MAGEB2 (MAGE family member B2)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41254/mageb2