MAGED2 (MAGE family member D2)

2003-11-01  

Identity

HGNC
MAGED2
LOCATION
Xp11.21
LOCUSID
10916
ALIAS
11B6,BARTS5,BCG-1,BCG1,HCA10,MAGE-D2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10916
MIM: 300470
HGNC: 16353
Ensembl: ENSG00000102316

Variants:

dbSNP: 10916
ClinVar: 10916
TCGA: ENSG00000102316
COSMIC: MAGED2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000102316ENST00000218439Q9UNF1
ENSG00000102316ENST00000218439A0A024R9Y7
ENSG00000102316ENST00000347546Q5H909
ENSG00000102316ENST00000375053Q9UNF1
ENSG00000102316ENST00000375053A0A024R9Y7
ENSG00000102316ENST00000375058Q9UNF1
ENSG00000102316ENST00000375058A0A024R9Y7
ENSG00000102316ENST00000375060Q5H907
ENSG00000102316ENST00000375068Q9UNF1
ENSG00000102316ENST00000375068A0A024R9Y7
ENSG00000102316ENST00000396224Q9UNF1
ENSG00000102316ENST00000396224A0A024R9Y7
ENSG00000102316ENST00000627068Q5H907

Expression (GTEx)

0
50
100
150
200
250
300
350
400
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
HemostasisREACTOMER-HSA-109582
Platelet activation, signaling and aggregationREACTOMER-HSA-76002
Response to elevated platelet cytosolic Ca2+REACTOMER-HSA-76005
Platelet degranulationREACTOMER-HSA-114608

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
381286472024Proteomic Analysis Revealed the Potential Role of MAGE-D2 in the Therapeutic Targeting of Triple-Negative Breast Cancer.2
382388442024Identification of a novel intronic mutation of MAGED2 gene in a Chinese family with antenatal Bartter syndrome.1
381286472024Proteomic Analysis Revealed the Potential Role of MAGE-D2 in the Therapeutic Targeting of Triple-Negative Breast Cancer.2
382388442024Identification of a novel intronic mutation of MAGED2 gene in a Chinese family with antenatal Bartter syndrome.1
376862372023MAGED2 Depletion Promotes Stress-Induced Autophagy by Impairing the cAMP/PKA Pathway.2
376862372023MAGED2 Depletion Promotes Stress-Induced Autophagy by Impairing the cAMP/PKA Pathway.2
347751002022MAGED2 controls vasopressin-induced aquaporin-2 expression in collecting duct cells.1
363598192022Reciprocal Regulation of MAGED2 and HIF-1α Augments Their Expression under Hypoxia: Role of cAMP and PKA Type II.3
347751002022MAGED2 controls vasopressin-induced aquaporin-2 expression in collecting duct cells.1
363598192022Reciprocal Regulation of MAGED2 and HIF-1α Augments Their Expression under Hypoxia: Role of cAMP and PKA Type II.3
291467022018Prevalence of Novel MAGED2 Mutations in Antenatal Bartter Syndrome.22
296770052018MAGED2: a novel form of antenatal Bartter's syndrome.10
291467022018Prevalence of Novel MAGED2 Mutations in Antenatal Bartter Syndrome.22
296770052018MAGED2: a novel form of antenatal Bartter's syndrome.10
257433302016The Expression of Melanoma-Associated Antigen D2 Both in Surgically Resected and Serum Samples Serves as Clinically Relevant Biomarker of Gastric Cancer Progression.19

Citation

Dessen P

MAGED2 (MAGE family member D2)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/41262/deep-insight-explorer/css/favicon/favicon-16x16.png