Identity
HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
CHK,CTK,HHYLTK,HYL,HYLTK,Lsk
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4145
MIM: 600038
HGNC: 6906
Ensembl: ENSG00000007264
Variants:
dbSNP: 4145
ClinVar: 4145
TCGA: ENSG00000007264
COSMIC: MATK
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 21799000 | 2011 | IGF-I stimulates cooperative interaction between the IGF-I receptor and CSK homologous kinase that regulates SHPS-1 phosphorylation in vascular smooth muscle cells. | 14 |
| 21799000 | 2011 | IGF-I stimulates cooperative interaction between the IGF-I receptor and CSK homologous kinase that regulates SHPS-1 phosphorylation in vascular smooth muscle cells. | 14 |
| 17934522 | 2008 | Decreased CHK protein levels are associated with Src activation in colon cancer cells. | 12 |
| 18292939 | 2008 | Csk homologous kinase inhibits CXCL12-CXCR4 signaling in neuroblastoma. | 0 |
| 17934522 | 2008 | Decreased CHK protein levels are associated with Src activation in colon cancer cells. | 12 |
| 18292939 | 2008 | Csk homologous kinase inhibits CXCL12-CXCR4 signaling in neuroblastoma. | 0 |
| 17492661 | 2007 | Progesterone increases csk homologous kinase in HMC-1560 human mast cells and reduces cell proliferation. | 2 |
| 17492661 | 2007 | Progesterone increases csk homologous kinase in HMC-1560 human mast cells and reduces cell proliferation. | 2 |
| 16168623 | 2006 | Csk homologous kinase (CHK), unlike Csk, enhances MAPK activation via Ras-mediated signaling in a Src-independent manner. | 3 |
| 16574955 | 2006 | Identification of the nonreceptor tyrosine kinase MATK/CHK as an essential regulator of immune cells using Matk/CHK-deficient mice. | 13 |
| 16707123 | 2006 | Involvement of the N-terminal unique domain of Chk tyrosine kinase in Chk-induced tyrosine phosphorylation in the nucleus. | 10 |
| 16168623 | 2006 | Csk homologous kinase (CHK), unlike Csk, enhances MAPK activation via Ras-mediated signaling in a Src-independent manner. | 3 |
| 16574955 | 2006 | Identification of the nonreceptor tyrosine kinase MATK/CHK as an essential regulator of immune cells using Matk/CHK-deficient mice. | 13 |
| 16707123 | 2006 | Involvement of the N-terminal unique domain of Chk tyrosine kinase in Chk-induced tyrosine phosphorylation in the nucleus. | 10 |
| 15748901 | 2005 | Multi-lobulation of the nucleus in prolonged S phase by nuclear expression of Chk tyrosine kinase. | 13 |
Citation
Dessen P
MATK (megakaryocyte-associated tyrosine kinase)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41305/matk
