MCTS1 (MCTS1 re-initiation and release factor)

2003-02-01  

Identity

HGNC
MCTS1
LOCATION
Xq24
LOCUSID
28985
ALIAS
MCT-1,MCT1

Other Information

Locus ID:

NCBI: 28985
MIM: 300587
HGNC: 23357
Ensembl: ENSG00000232119

Variants:

dbSNP: 28985
ClinVar: 28985
TCGA: ENSG00000232119
COSMIC: MCTS1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000232119ENST00000371315Q9ULC4
ENSG00000232119ENST00000371317Q9ULC4

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
376344102023MCTS1 enhances the proliferation of laryngeal squamous cell carcinoma via promoting OTUD6B-1 mediated LIN28B deubiquitination.0
378751082023Human MCTS1-dependent translation of JAK2 is essential for IFN-γ immunity to mycobacteria.7
376344102023MCTS1 enhances the proliferation of laryngeal squamous cell carcinoma via promoting OTUD6B-1 mediated LIN28B deubiquitination.0
378751082023Human MCTS1-dependent translation of JAK2 is essential for IFN-γ immunity to mycobacteria.7
352747602022MCTS1 promotes laryngeal squamous cell carcinoma cell growth via enhancing LARP7 stability.4
352747602022MCTS1 promotes laryngeal squamous cell carcinoma cell growth via enhancing LARP7 stability.4
346685212021MCT1 expression is independently related to shorter cancer-specific survival in clear cell renal cell carcinoma.4
347048202021Prognostic value of malignant T cell-amplified sequence 1 in head and neck squamous cell carcinoma.1
346685212021MCT1 expression is independently related to shorter cancer-specific survival in clear cell renal cell carcinoma.4
347048202021Prognostic value of malignant T cell-amplified sequence 1 in head and neck squamous cell carcinoma.1
305840922019Crystal structure of the DENR-MCT-1 complex revealed zinc-binding site essential for heterodimer formation.13
308852322019MCT-1/miR-34a/IL-6/IL-6R signaling axis promotes EMT progression, cancer stemness and M2 macrophage polarization in triple-negative breast cancer.192
318915692019Multiple Copies in T-Cell Malignancy 1 (MCT-1) Promotes the Stemness of Non-Small Cell Lung Cancer Cells via Activating Interleukin-6 (IL-6) Signaling through Suppressing MiR-34a Expression.4
305840922019Crystal structure of the DENR-MCT-1 complex revealed zinc-binding site essential for heterodimer formation.13
308852322019MCT-1/miR-34a/IL-6/IL-6R signaling axis promotes EMT progression, cancer stemness and M2 macrophage polarization in triple-negative breast cancer.192

Citation

Dessen P

MCTS1 (MCTS1 re-initiation and release factor)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41324