MEIS2 (Meis homeobox 2)

2003-02-01  

Identity

HGNC
MEIS2
LOCATION
15q14
LOCUSID
4212
ALIAS
CPCMR,HsT18361,MRG1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4212
MIM: 601740
HGNC: 7001
Ensembl: ENSG00000134138

Variants:

dbSNP: 4212
ClinVar: 4212
TCGA: ENSG00000134138
COSMIC: MEIS2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000134138ENST00000314177O14770
ENSG00000134138ENST00000314177A0A024R9J1
ENSG00000134138ENST00000338564O14770
ENSG00000134138ENST00000338564A0A024R9L4
ENSG00000134138ENST00000340545O14770
ENSG00000134138ENST00000397620O14770
ENSG00000134138ENST00000397624O14770
ENSG00000134138ENST00000424352O14770
ENSG00000134138ENST00000557796O14770
ENSG00000134138ENST00000558313H0YMX5
ENSG00000134138ENST00000559085O14770
ENSG00000134138ENST00000559561O14770
ENSG00000134138ENST00000560570H0YM65
ENSG00000134138ENST00000560617H0YKN2
ENSG00000134138ENST00000560697H0YKE5
ENSG00000134138ENST00000561208O14770
ENSG00000134138ENST00000606653U3KQ95
ENSG00000134138ENST00000607277U3KQI2

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
376609942024LINC-PINT suppresses breast cancer cell proliferation and migration via MEIS2/PPP3CC/NF-κB pathway by sponging miR-576-5p.0
381532332024Cellular Ligand-Receptor Perturbations Unravel MEIS2 as a Key Factor for the Aggressive Progression and Prognosis in Stage II/III Colorectal Cancer.0
383476322024Novel genetic markers for chronic kidney disease in a geographically isolated population of Indigenous Australians: Individual and multiple phenotype genome-wide association study.0
387112622024MEIS2 suppresses breast cancer development by downregulating IL10.1
376609942024LINC-PINT suppresses breast cancer cell proliferation and migration via MEIS2/PPP3CC/NF-κB pathway by sponging miR-576-5p.0
381532332024Cellular Ligand-Receptor Perturbations Unravel MEIS2 as a Key Factor for the Aggressive Progression and Prognosis in Stage II/III Colorectal Cancer.0
383476322024Novel genetic markers for chronic kidney disease in a geographically isolated population of Indigenous Australians: Individual and multiple phenotype genome-wide association study.0
387112622024MEIS2 suppresses breast cancer development by downregulating IL10.1
368409462023CircDHRS3 inhibits prostate cancer cell proliferation and metastasis through the circDHRS3/miR-421/MEIS2 axis.3
368409462023CircDHRS3 inhibits prostate cancer cell proliferation and metastasis through the circDHRS3/miR-421/MEIS2 axis.3
361138312022IGF2BP2 promotes the progression of ovarian endometriosis by regulating m6A-modified MEIS2 and GATA6.6
361138312022IGF2BP2 promotes the progression of ovarian endometriosis by regulating m6A-modified MEIS2 and GATA6.6
330912112021MEIS2 sequence variant in a child with intellectual disability and cardiac defects: Expansion of the phenotypic spectrum and documentation of low-level mosaicism in an unaffected parent.1
334273972021Intellectual disability associated with craniofacial dysmorphism, cleft palate, and congenital heart defect due to a de novo MEIS2 mutation: A clinical longitudinal study.2
338641102021Expression of ISL1 and its partners in prostate cancer progression and neuroendocrine differentiation.1

Citation

Dessen P

MEIS2 (Meis homeobox 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41332