MGAT5 (alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase)
2003-08-01 AffiliationIdentity
HGNC
LOCATION
2q21.2
LOCUSID
ALIAS
GNT-V,GNT-VA,MGAT5A,glcNAc-T
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4249
MIM: 601774
HGNC: 7049
Ensembl: ENSG00000152127
Variants:
dbSNP: 4249
ClinVar: 4249
TCGA: ENSG00000152127
COSMIC: MGAT5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000152127 | ENST00000281923 | Q09328 |
| ENSG00000152127 | ENST00000409645 | Q09328 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38499842 | 2024 | GnT-V-mediated aberrant N-glycosylation of TIMP-1 promotes diabetic retinopathy progression. | 0 |
| 38499842 | 2024 | GnT-V-mediated aberrant N-glycosylation of TIMP-1 promotes diabetic retinopathy progression. | 0 |
| 36689079 | 2023 | Aberrant N-glycosylation in cancer: MGAT5 and β1,6-GlcNAc branched N-glycans as critical regulators of tumor development and progression. | 7 |
| 36689079 | 2023 | Aberrant N-glycosylation in cancer: MGAT5 and β1,6-GlcNAc branched N-glycans as critical regulators of tumor development and progression. | 7 |
| 35104505 | 2022 | N-acetylglucosaminyltransferase-V requires a specific noncatalytic luminal domain for its activity toward glycoprotein substrates. | 7 |
| 35104505 | 2022 | N-acetylglucosaminyltransferase-V requires a specific noncatalytic luminal domain for its activity toward glycoprotein substrates. | 7 |
| 33879098 | 2021 | The polymorphisms of FGFR2 and MGAT5 affect the susceptibility to COPD in the Chinese people. | 4 |
| 33894774 | 2021 | Glioma stem cells invasive phenotype at optimal stiffness is driven by MGAT5 dependent mechanosensing. | 14 |
| 33879098 | 2021 | The polymorphisms of FGFR2 and MGAT5 affect the susceptibility to COPD in the Chinese people. | 4 |
| 33894774 | 2021 | Glioma stem cells invasive phenotype at optimal stiffness is driven by MGAT5 dependent mechanosensing. | 14 |
| 32352685 | 2020 | Genetic Variants of the MGAT5 Gene Are Functionally Implicated in the Modulation of T Cells Glycosylation and Plasma IgG Glycome Composition in Ulcerative Colitis. | 14 |
| 32890705 | 2020 | Recognition of glycan and protein substrates by N-acetylglucosaminyltransferase-V. | 8 |
| 32945502 | 2020 | N‑glycosylation and receptor tyrosine kinase signaling affect claudin‑3 levels in colorectal cancer cells. | 10 |
| 32352685 | 2020 | Genetic Variants of the MGAT5 Gene Are Functionally Implicated in the Modulation of T Cells Glycosylation and Plasma IgG Glycome Composition in Ulcerative Colitis. | 14 |
| 32890705 | 2020 | Recognition of glycan and protein substrates by N-acetylglucosaminyltransferase-V. | 8 |
Citation
Dessen P
MGAT5 (alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/41349/mgat5
