Identity
HGNC
LOCATION
1p35.1
LOCUSID
ALIAS
F52,MACMARCKS,MLP,MLP1,MRP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 65108
MIM: 602940
HGNC: 7142
Ensembl: ENSG00000175130
Variants:
dbSNP: 65108
ClinVar: 65108
TCGA: ENSG00000175130
COSMIC: MARCKSL1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000175130 | ENST00000329421 | P49006 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Fc gamma R-mediated phagocytosis | KEGG | ko04666 |
| Fc gamma R-mediated phagocytosis | KEGG | hsa04666 |
| Leishmaniasis | KEGG | ko05140 |
| Leishmaniasis | KEGG | hsa05140 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35894387 | 2023 | MARCKSL1 interacted with F-actin to promote esophageal squamous cell carcinoma mobility by modulating the formation of invadopodia. | 4 |
| 37340044 | 2023 | Circulating extracellular vesicle-derived MARCKSL1 is a potential diagnostic non-invasive biomarker in metastatic colorectal cancer patients. | 1 |
| 35894387 | 2023 | MARCKSL1 interacted with F-actin to promote esophageal squamous cell carcinoma mobility by modulating the formation of invadopodia. | 4 |
| 37340044 | 2023 | Circulating extracellular vesicle-derived MARCKSL1 is a potential diagnostic non-invasive biomarker in metastatic colorectal cancer patients. | 1 |
| 34586620 | 2022 | METTL14-Mediated miR-30c-1-3p Maturation Represses the Progression of Lung Cancer via Regulation of MARCKSL1 Expression. | 7 |
| 35864549 | 2022 | MARCKSL1-2 reverses docetaxel-resistance of lung adenocarcinoma cells by recruiting SUZ12 to suppress HDAC1 and elevate miR-200b. | 17 |
| 36374807 | 2022 | IncRNA TYMSOS Promotes Epithelial-Mesenchymal Transition and Metastasis in Thyroid Carcinoma through Regulating MARCKSL1 and Activating the PI3K/Akt Signaling Pathway. | 3 |
| 34586620 | 2022 | METTL14-Mediated miR-30c-1-3p Maturation Represses the Progression of Lung Cancer via Regulation of MARCKSL1 Expression. | 7 |
| 35864549 | 2022 | MARCKSL1-2 reverses docetaxel-resistance of lung adenocarcinoma cells by recruiting SUZ12 to suppress HDAC1 and elevate miR-200b. | 17 |
| 36374807 | 2022 | IncRNA TYMSOS Promotes Epithelial-Mesenchymal Transition and Metastasis in Thyroid Carcinoma through Regulating MARCKSL1 and Activating the PI3K/Akt Signaling Pathway. | 3 |
| 30856208 | 2019 | Validation study of MARCKSL1 as a prognostic factor in lymph node-negative breast cancer patients. | 5 |
| 31155484 | 2019 | Direct Reprogramming of Human Neurons Identifies MARCKSL1 as a Pathogenic Mediator of Valproic Acid-Induced Teratogenicity. | 28 |
| 30856208 | 2019 | Validation study of MARCKSL1 as a prognostic factor in lymph node-negative breast cancer patients. | 5 |
| 31155484 | 2019 | Direct Reprogramming of Human Neurons Identifies MARCKSL1 as a Pathogenic Mediator of Valproic Acid-Induced Teratogenicity. | 28 |
| 26555156 | 2016 | MARCKSL1 exhibits anti-angiogenic effects through suppression of VEGFR-2-dependent Akt/PDK-1/mTOR phosphorylation. | 7 |
Citation
Dessen P
MARCKSL1 (MARCKS like 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/41380/marcksl1
