Identity
HGNC
LOCATION
11q22.2
LOCUSID
ALIAS
CLG3,MANDP1,MDST,MMP-13
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4322
MIM: 600108
HGNC: 7159
Ensembl: ENSG00000137745
Variants:
dbSNP: 4322
ClinVar: 4322
TCGA: ENSG00000137745
COSMIC: MMP13
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000137745 | ENST00000260302 | P45452 |
| ENSG00000137745 | ENST00000340273 | G5E971 |
| ENSG00000137745 | ENST00000615555 | Q7Z5M0 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37489792 | 2024 | The Mediating Role of miR-451/ETV4/MMP13 Signaling Axis on Epithelialmesenchymal Transition in Promoting Non-small Cell Lung Cancer Progression. | 0 |
| 38251858 | 2024 | Breast cancer malignancy is governed by regulation of the macroH2A2/TM4SF1 axis, the AKT/NF-κB pathway, and elevated MMP13 expression. | 0 |
| 38471488 | 2024 | Human Host Defense Peptide LL-37 Suppresses TNFα-Mediated Matrix Metalloproteinases MMP9 and MMP13 in Human Bronchial Epithelial Cells. | 0 |
| 38527983 | 2024 | MMP1, MMP9, MMP11 and MMP13 in melanoma and its metastasis - key points in understanding the mechanisms and celerity of tumor dissemination. | 1 |
| 38619683 | 2024 | Inhibiting MMP13 Attenuates Deep Vein Thrombosis in a Mouse Model by Reducing the Expression of Pdpn. | 1 |
| 38770093 | 2024 | TPX2 upregulates MMP13 to promote the progression of lipopolysaccharide-induced osteoarthritis. | 1 |
| 38936942 | 2024 | Association of Clinicopathological Factors With MMP13 (rs2252070) Gene Polymorphism in Swedish Patients With Colorectal Cancer. | 0 |
| 37489792 | 2024 | The Mediating Role of miR-451/ETV4/MMP13 Signaling Axis on Epithelialmesenchymal Transition in Promoting Non-small Cell Lung Cancer Progression. | 0 |
| 38251858 | 2024 | Breast cancer malignancy is governed by regulation of the macroH2A2/TM4SF1 axis, the AKT/NF-κB pathway, and elevated MMP13 expression. | 0 |
| 38471488 | 2024 | Human Host Defense Peptide LL-37 Suppresses TNFα-Mediated Matrix Metalloproteinases MMP9 and MMP13 in Human Bronchial Epithelial Cells. | 0 |
| 38527983 | 2024 | MMP1, MMP9, MMP11 and MMP13 in melanoma and its metastasis - key points in understanding the mechanisms and celerity of tumor dissemination. | 1 |
| 38619683 | 2024 | Inhibiting MMP13 Attenuates Deep Vein Thrombosis in a Mouse Model by Reducing the Expression of Pdpn. | 1 |
| 38770093 | 2024 | TPX2 upregulates MMP13 to promote the progression of lipopolysaccharide-induced osteoarthritis. | 1 |
| 38936942 | 2024 | Association of Clinicopathological Factors With MMP13 (rs2252070) Gene Polymorphism in Swedish Patients With Colorectal Cancer. | 0 |
| 36409042 | 2023 | Increased expression of angiopoietin-like protein 4 regulates matrix metalloproteinase-13 expression in Porphyromonas gingivalis lipopolysaccharides-stimulated gingival fibroblasts and ligature-induced experimental periodontitis. | 1 |
Citation
Dessen P
MMP13 (matrix metallopeptidase 13)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41390/mmp13
