MMP20 (matrix metallopeptidase 20)

2003-06-01  

Identity

HGNC
MMP20
LOCATION
11q22.2
LOCUSID
9313
ALIAS
AI2A2,MMP-20
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9313
MIM: 604629
HGNC: 7167
Ensembl: ENSG00000137674

Variants:

dbSNP: 9313
ClinVar: 9313
TCGA: ENSG00000137674
COSMIC: MMP20

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137674ENST00000260228O60882

Expression (GTEx)

0
1
2
3
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Extracellular matrix organizationREACTOMER-HSA-1474244
Collagen formationREACTOMER-HSA-1474290
Assembly of collagen fibrils and other multimeric structuresREACTOMER-HSA-2022090
Degradation of the extracellular matrixREACTOMER-HSA-1474228
Collagen degradationREACTOMER-HSA-1442490

References

Pubmed IDYearTitleCitations
339147772021Lung development, repair and cancer: A study on the role of MMP20 gene in adenocarcinoma.2
339147772021Lung development, repair and cancer: A study on the role of MMP20 gene in adenocarcinoma.2
318382952020DNA sequencing reveals AMELX, ODAM and MMP20 variations in dental fluorosis.5
324955032020Dental malformations associated with biallelic MMP20 mutations.4
327775812020The possible influence of genetic aetiological factors on molar-incisor hypomineralisation.9
318382952020DNA sequencing reveals AMELX, ODAM and MMP20 variations in dental fluorosis.5
324955032020Dental malformations associated with biallelic MMP20 mutations.4
327775812020The possible influence of genetic aetiological factors on molar-incisor hypomineralisation.9
306399792019Evaluation of genetic polymorphisms in MMP2, MMP9 and MMP20 in Brazilian children with dental fluorosis.3
309323692019Survey of dentin sialophosphoprotein and its cognate matrix metalloproteinase-20 in human cancers.6
311067812019MMP20 Single-Nucleotide Polymorphisms Correlate with Susceptibility to Alcohol-Induced Osteonecrosis of the Femoral Head in Chinese Males.3
306399792019Evaluation of genetic polymorphisms in MMP2, MMP9 and MMP20 in Brazilian children with dental fluorosis.3
309323692019Survey of dentin sialophosphoprotein and its cognate matrix metalloproteinase-20 in human cancers.6
311067812019MMP20 Single-Nucleotide Polymorphisms Correlate with Susceptibility to Alcohol-Induced Osteonecrosis of the Femoral Head in Chinese Males.3
300026822018DSPP-MMP20 gene silencing downregulates cancer stem cell markers in human oral cancer cells.8

Citation

Dessen P

MMP20 (matrix metallopeptidase 20)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/41397