MT1H (metallothionein 1H)

2003-08-01  

Identity

HGNC
MT1H
LOCATION
16q13
LOCUSID
4496
ALIAS
MT-0,MT-1H,MT-IH,MT1

Other Information

Locus ID:

NCBI: 4496
MIM: 156354
HGNC: 7400
Ensembl: ENSG00000205358

Variants:

dbSNP: 4496
ClinVar: 4496
TCGA: ENSG00000205358
COSMIC: MT1H

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000205358ENST00000332374P80294
ENSG00000205358ENST00000332374A0A140VJP7
ENSG00000205358ENST00000569155H3BTC4

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Mineral absorptionKEGGko04978
Mineral absorptionKEGGhsa04978
MetabolismREACTOMER-HSA-1430728
Response to metal ionsREACTOMER-HSA-5660526
Metallothioneins bind metalsREACTOMER-HSA-5661231

References

Pubmed IDYearTitleCitations
282418062017Metallothionein 1H (MT1H) functions as a tumor suppressor in hepatocellular carcinoma through regulating Wnt/β-catenin signaling pathway.28
282418062017Metallothionein 1H (MT1H) functions as a tumor suppressor in hepatocellular carcinoma through regulating Wnt/β-catenin signaling pathway.28
246627362015An epigenetic screen unmasks metallothioneins as putative contributors to renal cell carcinogenesis.4
246627362015An epigenetic screen unmasks metallothioneins as putative contributors to renal cell carcinogenesis.4
205512112010Increased metallothionein gene expression, zinc, and zinc-dependent resistance to apoptosis in circulating monocytes during HIV viremia.22
205512112010Increased metallothionein gene expression, zinc, and zinc-dependent resistance to apoptosis in circulating monocytes during HIV viremia.22
157477762003Dose-dependent transcriptome changes by metal ores on a human acute lymphoblastic leukemia cell line.3
157477762003Dose-dependent transcriptome changes by metal ores on a human acute lymphoblastic leukemia cell line.3
120814842002S-nitrosothiols react preferentially with zinc thiolate clusters of metallothionein III through transnitrosation.20
120814842002S-nitrosothiols react preferentially with zinc thiolate clusters of metallothionein III through transnitrosation.20

Citation

Dessen P

MT1H (metallothionein 1H)

Atlas Genet Cytogenet Oncol Haematol. 2003-08-01

Online version: http://atlasgeneticsoncology.org/gene/41440