MYCNOS (MYCN opposite strand)

2003-06-01 Affiliation

Identity

HGNC

MYCNOS

LOCATION

2p24.3

LOCUSID

10408

ALIAS

MYCN-AS1,N-CYM,NCYM,NYCM

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 10408
MIM: 605374
HGNC: 16911
Ensembl: ENSG00000233718

Variants:

dbSNP: 10408
ClinVar: 10408
TCGA: ENSG00000233718
COSMIC: MYCNOS

RNA/Proteins

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
32577751	2020	De novo evolved gene product NCYM in the pathogenesis and clinical outcome of human neuroblastomas and other cancers.	12
32577751	2020	De novo evolved gene product NCYM in the pathogenesis and clinical outcome of human neuroblastomas and other cancers.	12
30864675	2019	Targeting excessive MYCN expression using MLN8237 and JQ1 impairs the growth of hepatoblastoma cells.	4
31427086	2019	TAp63 represses transcription of MYCN/NCYM gene and its high levels of expression are associated with favorable outcome in neuroblastoma.	7
30864675	2019	Targeting excessive MYCN expression using MLN8237 and JQ1 impairs the growth of hepatoblastoma cells.	4
31427086	2019	TAp63 represses transcription of MYCN/NCYM gene and its high levels of expression are associated with favorable outcome in neuroblastoma.	7
29466962	2018	The long non-coding RNA MYCNOS-01 regulates MYCN protein levels and affects growth of MYCN-amplified rhabdomyosarcoma and neuroblastoma cells.	18
29772237	2018	LSINCT5 activates Wnt/β-catenin signaling by interacting with NCYM to promote bladder cancer progression.	17
29466962	2018	The long non-coding RNA MYCNOS-01 regulates MYCN protein levels and affects growth of MYCN-amplified rhabdomyosarcoma and neuroblastoma cells.	18
29772237	2018	LSINCT5 activates Wnt/β-catenin signaling by interacting with NCYM to promote bladder cancer progression.	17
27748806	2016	NCYM is upregulated by lncUSMycN and modulates N-Myc expression.	17
27748806	2016	NCYM is upregulated by lncUSMycN and modulates N-Myc expression.	17
25880909	2015	Functional interplay between MYCN, NCYM, and OCT4 promotes aggressiveness of human neuroblastomas.	27
25880909	2015	Functional interplay between MYCN, NCYM, and OCT4 promotes aggressiveness of human neuroblastomas.	27
24391509	2014	NCYM, a Cis-antisense gene of MYCN, encodes a de novo evolved protein that inhibits GSK3β resulting in the stabilization of MYCN in human neuroblastomas.	45

Citation

Dessen P

MYCNOS (MYCN opposite strand)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/41474