MYO18B (myosin XVIIIB)

2003-02-01 Affiliation

Identity

HGNC

MYO18B

LOCATION

22q12.1

LOCUSID

84700

ALIAS

KFS4

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 84700
MIM: 607295
HGNC: 18150
Ensembl: ENSG00000133454

Variants:

dbSNP: 84700
ClinVar: 84700
TCGA: ENSG00000133454
COSMIC: MYO18B

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000133454	ENST00000335473	Q8IUG5
ENSG00000133454	ENST00000407587	Q8IUG5
ENSG00000133454	ENST00000536101	Q8IUG5
ENSG00000133454	ENST00000539302	F5H6I8
ENSG00000133454	ENST00000540454	A0A2Q2TCQ6
ENSG00000133454	ENST00000543971	H0YGQ4

Expression (GTEx)

100

150

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
33179433	2021	Further delineation of MYO18B-related autosomal recessive Klippel-Feil syndrome with myopathy and facial dysmorphism.	0
33555505	2021	Myosin18B predicts favorable prognosis of cutaneous squamous-cell carcinoma.	2
33179433	2021	Further delineation of MYO18B-related autosomal recessive Klippel-Feil syndrome with myopathy and facial dysmorphism.	0
33555505	2021	Myosin18B predicts favorable prognosis of cutaneous squamous-cell carcinoma.	2
32877672	2020	Myosin-18B Regulates Higher-Order Organization of the Cardiac Sarcomere through Thin Filament Cross-Linking and Thick Filament Dynamics.	6
32877672	2020	Myosin-18B Regulates Higher-Order Organization of the Cardiac Sarcomere through Thin Filament Cross-Linking and Thick Filament Dynamics.	6
30581023	2019	Myosin-18B Promotes the Assembly of Myosin II Stacks for Maturation of Contractile Actomyosin Bundles.	20
30581023	2019	Myosin-18B Promotes the Assembly of Myosin II Stacks for Maturation of Contractile Actomyosin Bundles.	20
30390677	2018	MYO18B promotes hepatocellular carcinoma progression by activating PI3K/AKT/mTOR signaling pathway.	10
30390677	2018	MYO18B promotes hepatocellular carcinoma progression by activating PI3K/AKT/mTOR signaling pathway.	10
28104788	2017	Myo18b is essential for sarcomere assembly in fast skeletal muscle.	15
28104788	2017	Myo18b is essential for sarcomere assembly in fast skeletal muscle.	15
25748484	2015	A novel syndrome of Klippel-Feil anomaly, myopathy, and characteristic facies is linked to a null mutation in MYO18B.	29
25778778	2015	Lack of replication for the myosin-18B association with mathematical ability in independent cohorts.	8
25748484	2015	A novel syndrome of Klippel-Feil anomaly, myopathy, and characteristic facies is linked to a null mutation in MYO18B.	29

Citation

Dessen P

MYO18B (myosin XVIIIB)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41481/teaching-explorer/gene-fusions/gene-fusions-explorer/