NELL1 (neural EGFL like 1)

2003-02-01  

Identity

HGNC
NELL1
LOCATION
11p15.1
LOCUSID
4745
ALIAS
IDH3GL,NRP1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4745
MIM: 602319
HGNC: 7750
Ensembl: ENSG00000165973

Variants:

dbSNP: 4745
ClinVar: 4745
TCGA: ENSG00000165973
COSMIC: NELL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000165973ENST00000298925J3KNC5
ENSG00000165973ENST00000325319F5H6I3
ENSG00000165973ENST00000357134Q92832
ENSG00000165973ENST00000532434Q92832

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
371570702023[Clinical Significance of Thrombospondin Type 1 Domain-Containing 7A and Neural Epidermal Growth Factor-Like 1 Protein in M-Type Phospholipase A2 Receptor-Negative Membranous Nephropathy].0
371570702023[Clinical Significance of Thrombospondin Type 1 Domain-Containing 7A and Neural Epidermal Growth Factor-Like 1 Protein in M-Type Phospholipase A2 Receptor-Negative Membranous Nephropathy].0
346473172022NELL1 augments osteogenesis and inhibits inflammation of human periodontal ligament stem cells induced by BMP9.4
348905562022NELL-1 in Genome-Wide Association Studies across Human Diseases.5
351941252022Prevalence of neural epidermal growth factor-like 1- and exostosin 1/exostosin 2-associated membranous nephropathy: a single-center retrospective study in Japan.14
357002632022NELL1 Regulates the Matrisome to Promote Osteosarcoma Progression.10
359402262022Conformational Change of the Hairpin-like-structured Robo2 Ectodomain Allows NELL1/2 Binding.0
361759522022Runx2 and Nell-1 in dental follicle progenitor cells regulate bone remodeling and tooth eruption.11
346473172022NELL1 augments osteogenesis and inhibits inflammation of human periodontal ligament stem cells induced by BMP9.4
348905562022NELL-1 in Genome-Wide Association Studies across Human Diseases.5
351941252022Prevalence of neural epidermal growth factor-like 1- and exostosin 1/exostosin 2-associated membranous nephropathy: a single-center retrospective study in Japan.14
357002632022NELL1 Regulates the Matrisome to Promote Osteosarcoma Progression.10
359402262022Conformational Change of the Hairpin-like-structured Robo2 Ectodomain Allows NELL1/2 Binding.0
361759522022Runx2 and Nell-1 in dental follicle progenitor cells regulate bone remodeling and tooth eruption.11
328287562021NELL1 is a target antigen in malignancy-associated membranous nephropathy.76

Citation

Dessen P

NELL1 (neural EGFL like 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41523/case-report-explorer/teaching-explorer/gene-explorer/