Identity
HGNC
LOCATION
17q21.1
LOCUSID
ALIAS
EAR1,REVERBA,REVERBalpha,THRA1,THRAL,ear-1,hRev
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9572
MIM: 602408
HGNC: 7962
Ensembl: ENSG00000126368
Variants:
dbSNP: 9572
ClinVar: 9572
TCGA: ENSG00000126368
COSMIC: NR1D1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000126368 | ENST00000246672 | P20393 |
| ENSG00000126368 | ENST00000246672 | F1D8S3 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA447199 | Bipolar Disorder | Disease | ClinicalAnnotation | associated | PD | 20348464 | |
| PA450243 | lithium | Chemical | ClinicalAnnotation | associated | PD | 20348464 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38084644 | 2024 | NR1D1-rearranged soft tissue tumour: A clinicopathological and molecular analysis of four additional cases. | 0 |
| 38255844 | 2024 | Functional Characterization of Circadian Nuclear Receptors REV-ERBα and REV-ERBβ in Human Osteosarcoma Cell Cultures. | 0 |
| 38748870 | 2024 | Nuclear receptor Rev-erbα role in fine-tuning erythropoietin gene expression. | 0 |
| 38084644 | 2024 | NR1D1-rearranged soft tissue tumour: A clinicopathological and molecular analysis of four additional cases. | 0 |
| 38255844 | 2024 | Functional Characterization of Circadian Nuclear Receptors REV-ERBα and REV-ERBβ in Human Osteosarcoma Cell Cultures. | 0 |
| 38748870 | 2024 | Nuclear receptor Rev-erbα role in fine-tuning erythropoietin gene expression. | 0 |
| 37208228 | 2023 | Clock gene NR1D1 might be a novel target for the treatment of bladder cancer. | 1 |
| 37762536 | 2023 | Uncovering the Novel Role of NR1D1 in Regulating BNIP3-Mediated Mitophagy in Ulcerative Colitis. | 2 |
| 38092833 | 2023 | Sex-dependent relationship of polymorphisms in CLOCK and REV-ERBα genes with body mass index and lipid levels in children. | 0 |
| 37208228 | 2023 | Clock gene NR1D1 might be a novel target for the treatment of bladder cancer. | 1 |
| 37762536 | 2023 | Uncovering the Novel Role of NR1D1 in Regulating BNIP3-Mediated Mitophagy in Ulcerative Colitis. | 2 |
| 38092833 | 2023 | Sex-dependent relationship of polymorphisms in CLOCK and REV-ERBα genes with body mass index and lipid levels in children. | 0 |
| 34861472 | 2022 | REV-ERBs negatively regulate mineralization of the cementoblasts. | 3 |
| 35880522 | 2022 | Nuclear Receptor NR1D1 Regulates Abdominal Aortic Aneurysm Development by Targeting the Mitochondrial Tricarboxylic Acid Cycle Enzyme Aconitase-2. | 14 |
| 34861472 | 2022 | REV-ERBs negatively regulate mineralization of the cementoblasts. | 3 |
Citation
Dessen P
NR1D1 (nuclear receptor subfamily 1 group D member 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/41569/nr1d1
