NR2F6 (nuclear receptor subfamily 2 group F member 6)

2003-02-01  

Identity

HGNC
NR2F6
LOCATION
19p13.11
LOCUSID
2063
ALIAS
EAR-2,EAR2,ERBAL2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 2063
MIM: 132880
HGNC: 7977
Ensembl: ENSG00000160113

Variants:

dbSNP: 2063
ClinVar: 2063
TCGA: ENSG00000160113
COSMIC: NR2F6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000160113ENST00000291442P10588
ENSG00000160113ENST00000291442F1D8R3
ENSG00000160113ENST00000596878M0R175

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Nuclear Receptor transcription pathwayREACTOMER-HSA-383280

References

Pubmed IDYearTitleCitations
385510712024UPK3A(+) umbrella cell damage mediated by TLR3-NR2F6 triggers programmed destruction of urothelium in Hunner-type interstitial cystitis/painful bladder syndrome.0
385510712024UPK3A(+) umbrella cell damage mediated by TLR3-NR2F6 triggers programmed destruction of urothelium in Hunner-type interstitial cystitis/painful bladder syndrome.0
368841152023Overexpression of the orphan nuclear receptor NR2F6 is associated with improved survival across molecular subgroups in endometrial cancer patients.0
375752372023NR2F6, a new immune checkpoint that acts as a potential biomarker of immunosuppression and contributes to poor clinical outcome in human glioma.1
368841152023Overexpression of the orphan nuclear receptor NR2F6 is associated with improved survival across molecular subgroups in endometrial cancer patients.0
375752372023NR2F6, a new immune checkpoint that acts as a potential biomarker of immunosuppression and contributes to poor clinical outcome in human glioma.1
343047152021Incomplete thermal ablation-induced up-regulation of transcription factor nuclear receptor subfamily 2, group F, member 6 (NR2F6) contributes to the rapid progression of residual liver tumor in hepatoblastoma.2
344722802021[The role of nuclear receptor transcription factor NR2F6 in tumor].1
343047152021Incomplete thermal ablation-induced up-regulation of transcription factor nuclear receptor subfamily 2, group F, member 6 (NR2F6) contributes to the rapid progression of residual liver tumor in hepatoblastoma.2
344722802021[The role of nuclear receptor transcription factor NR2F6 in tumor].1
322039342020Regulation of docetaxel chemosensitivity by NR2F6 in breast cancer.7
327522952020NR2F6 as a Prognostic Biomarker in HNSCC.11
322039342020Regulation of docetaxel chemosensitivity by NR2F6 in breast cancer.7
327522952020NR2F6 as a Prognostic Biomarker in HNSCC.11
308956192019Nuclear orphan receptor NR2F6 confers cisplatin resistance in epithelial ovarian cancer cells by activating the Notch3 signaling pathway.20

Citation

Dessen P

NR2F6 (nuclear receptor subfamily 2 group F member 6)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41572