NRDC (nardilysin convertase)

2015-11-01  

Identity

HGNC
NRDC
LOCATION
1p32.3
LOCUSID
4898
ALIAS
NRD1,hNRD1,hNRD2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4898
MIM: 602651
HGNC: 7995
Ensembl: ENSG00000078618

Variants:

dbSNP: 4898
ClinVar: 4898
TCGA: ENSG00000078618
COSMIC: NRDC

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000078618ENST00000352171O43847
ENSG00000078618ENST00000354831O43847
ENSG00000078618ENST00000440943H0Y5G9
ENSG00000078618ENST00000539524G3V1R5
ENSG00000078618ENST00000544028F5H7V1

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
386022372024CircNRD1 elevates THAP domain containing 11 through sequestering microRNA-421 to inhibit gastric cancer growth and tumorigenesis.0
386022372024CircNRD1 elevates THAP domain containing 11 through sequestering microRNA-421 to inhibit gastric cancer growth and tumorigenesis.0
358156872022Altered Levels of Negative Costimulatory Molecule V-Set Domain-Containing T-Cell Activation Inhibitor-1 (VTCN1) and Metalloprotease Nardilysin (NRD1) are Associated with Generalized Active Vitiligo.0
358156872022Altered Levels of Negative Costimulatory Molecule V-Set Domain-Containing T-Cell Activation Inhibitor-1 (VTCN1) and Metalloprotease Nardilysin (NRD1) are Associated with Generalized Active Vitiligo.0
305363412018Increased serum nardilysin is associated with worse long-term outcome of ST-elevation myocardial infarction.1
305363412018Increased serum nardilysin is associated with worse long-term outcome of ST-elevation myocardial infarction.1
287470152017Nardilysin is a promising biomarker for the early diagnosis of acute coronary syndrome.9
287470152017Nardilysin is a promising biomarker for the early diagnosis of acute coronary syndrome.9
269432372016Association of gene expression and methylation of UQCRC1 to the predisposition of Alzheimer's disease in a Chinese population.8
269432372016Association of gene expression and methylation of UQCRC1 to the predisposition of Alzheimer's disease in a Chinese population.8
241681652014NRD1, which encodes nardilysin protein, promotes esophageal cancer cell invasion through induction of MMP2 and MMP3 expression.13
241681652014NRD1, which encodes nardilysin protein, promotes esophageal cancer cell invasion through induction of MMP2 and MMP3 expression.13
232194612013Decreased expression of nardilysin in SH-SY5Y cells under ethanol stress and reduced density of nardilysin-expressing neurons in brains of alcoholics.0
236044052013Nardilysin in human brain diseases: both friend and foe.7
232194612013Decreased expression of nardilysin in SH-SY5Y cells under ethanol stress and reduced density of nardilysin-expressing neurons in brains of alcoholics.0

Citation

Dessen P

NRDC (nardilysin convertase)

Atlas Genet Cytogenet Oncol Haematol. 2015-11-01

Online version: http://atlasgeneticsoncology.org/gene/41579