Identity
HGNC
LOCATION
14q11.2
LOCUSID
ALIAS
OPMD,PAB2,PABII,PABP-2,PABP2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8106
MIM: 602279
HGNC: 8565
Ensembl: ENSG00000100836
Variants:
dbSNP: 8106
ClinVar: 8106
TCGA: ENSG00000100836
COSMIC: PABPN1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38244911 | 2024 | Dysregulation of RNA-Exosome machinery is directly linked to major cancer hallmarks in prostate cancer: Oncogenic role of PABPN1. | 0 |
| 38244911 | 2024 | Dysregulation of RNA-Exosome machinery is directly linked to major cancer hallmarks in prostate cancer: Oncogenic role of PABPN1. | 0 |
| 36754576 | 2023 | PABPN1 prevents the nuclear export of an unspliced RNA with a constitutive transport element and controls human gene expression via intron retention. | 4 |
| 37356722 | 2023 | The RNA-binding protein ZC3H11A interacts with the nuclear poly(A)-binding protein PABPN1 and alters polyadenylation of viral transcripts. | 2 |
| 37422193 | 2023 | PABPN1 aggregation is driven by Ala expansion and poly(A)-RNA binding, leading to CFIm25 sequestration that impairs alternative polyadenylation. | 1 |
| 36754576 | 2023 | PABPN1 prevents the nuclear export of an unspliced RNA with a constitutive transport element and controls human gene expression via intron retention. | 4 |
| 37356722 | 2023 | The RNA-binding protein ZC3H11A interacts with the nuclear poly(A)-binding protein PABPN1 and alters polyadenylation of viral transcripts. | 2 |
| 37422193 | 2023 | PABPN1 aggregation is driven by Ala expansion and poly(A)-RNA binding, leading to CFIm25 sequestration that impairs alternative polyadenylation. | 1 |
| 35025870 | 2022 | Activation of the ubiquitin-proteasome system contributes to oculopharyngeal muscular dystrophy through muscle atrophy. | 9 |
| 35894779 | 2022 | Novel read-through fusion transcript Bcl2l2-Pabpn1 in glioblastoma cells. | 5 |
| 36197469 | 2022 | Assessment of PABPN1 nuclear inclusions on a large cohort of patients and in a human xenograft model of oculopharyngeal muscular dystrophy. | 4 |
| 35025870 | 2022 | Activation of the ubiquitin-proteasome system contributes to oculopharyngeal muscular dystrophy through muscle atrophy. | 9 |
| 35894779 | 2022 | Novel read-through fusion transcript Bcl2l2-Pabpn1 in glioblastoma cells. | 5 |
| 36197469 | 2022 | Assessment of PABPN1 nuclear inclusions on a large cohort of patients and in a human xenograft model of oculopharyngeal muscular dystrophy. | 4 |
| 33467093 | 2021 | Regulation of Kv11.1 Isoform Expression by Polyadenylate Binding Protein Nuclear 1. | 4 |
Citation
Dessen P
PABPN1 (poly(A) binding protein nuclear 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/41629/pabpn1
