Identity
HGNC
LOCATION
3p24.3
LOCUSID
ALIAS
CAF,P/CAF,PCAF
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8850
MIM: 602303
HGNC: 8638
Ensembl: ENSG00000114166
Variants:
dbSNP: 8850
ClinVar: 8850
TCGA: ENSG00000114166
COSMIC: KAT2B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000114166 | ENST00000263754 | Q92831 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA131890620 | cannabinoids | Chemical | ClinicalAnnotation | associated | PD | ||
| PA446876 | Substance-Related Disorders | Disease | ClinicalAnnotation | associated | PD | ||
| PA448408 | amphetamine | Chemical | ClinicalAnnotation | associated | PD | ||
| PA449072 | cocaine | Chemical | ClinicalAnnotation | associated | PD | ||
| PA452618 | opioids | Chemical | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38641672 | 2024 | The histone lysine acetyltransferase KAT2B inhibits cholangiocarcinoma growth: evidence for interaction with SP1 to regulate NF2-YAP signaling. | 0 |
| 38641672 | 2024 | The histone lysine acetyltransferase KAT2B inhibits cholangiocarcinoma growth: evidence for interaction with SP1 to regulate NF2-YAP signaling. | 0 |
| 36104638 | 2023 | Upregulation of KAT2B and ESCO2 gene expression level in patients with rheumatoid arthritis. | 2 |
| 37117180 | 2023 | Dependency of NELF-E-SLUG-KAT2B epigenetic axis in breast cancer carcinogenesis. | 0 |
| 36104638 | 2023 | Upregulation of KAT2B and ESCO2 gene expression level in patients with rheumatoid arthritis. | 2 |
| 37117180 | 2023 | Dependency of NELF-E-SLUG-KAT2B epigenetic axis in breast cancer carcinogenesis. | 0 |
| 34270849 | 2022 | Acetylation of the influenza A virus polymerase subunit PA in the N-terminal domain positively regulates its endonuclease activity. | 7 |
| 35848906 | 2022 | N4BP3 promotes angiogenesis in hepatocellular carcinoma by binding with KAT2B. | 3 |
| 36246398 | 2022 | PCAF Accelerates Vascular Senescence via the Hippo Signaling Pathway. | 1 |
| 36293441 | 2022 | Downregulation of P300/CBP-Associated Factor Protects from Vascular Aging via Nrf2 Signal Pathway Activation. | 3 |
| 34270849 | 2022 | Acetylation of the influenza A virus polymerase subunit PA in the N-terminal domain positively regulates its endonuclease activity. | 7 |
| 35848906 | 2022 | N4BP3 promotes angiogenesis in hepatocellular carcinoma by binding with KAT2B. | 3 |
| 36246398 | 2022 | PCAF Accelerates Vascular Senescence via the Hippo Signaling Pathway. | 1 |
| 36293441 | 2022 | Downregulation of P300/CBP-Associated Factor Protects from Vascular Aging via Nrf2 Signal Pathway Activation. | 3 |
| 33310188 | 2021 | Histone acetyltransferase p300 mediates the upregulation of CTEN induced by the activation of EGFR signaling in cancer cells. | 4 |
Citation
Dessen P
KAT2B (lysine acetyltransferase 2B)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41654/kat2b
