ANO7 (anoctamin 7)

2003-02-01  

Identity

HGNC
ANO7
LOCATION
2q37.3
LOCUSID
50636
ALIAS
D-TMPP,DTMPP,IPCA-5,IPCA5,NGEP,PCANAP5,PCANAP5L,TMEM16G
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 50636
MIM: 605096
HGNC: 31677
Ensembl: ENSG00000146205

Variants:

dbSNP: 50636
ClinVar: 50636
TCGA: ENSG00000146205
COSMIC: ANO7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000146205ENST00000274979Q6IWH7
ENSG00000146205ENST00000402430Q6IWH7
ENSG00000146205ENST00000402530Q6IWH7
ENSG00000146205ENST00000451047H7C220

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
Ion channel transportREACTOMER-HSA-983712
Stimuli-sensing channelsREACTOMER-HSA-2672351

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
366745642023Transcripts of the Prostate Cancer-Associated Gene ANO7 Are Retained in the Nuclei of Prostatic Epithelial Cells.0
366745642023Transcripts of the Prostate Cancer-Associated Gene ANO7 Are Retained in the Nuclei of Prostatic Epithelial Cells.0
350439582022The variant rs77559646 associated with aggressive prostate cancer disrupts ANO7 mRNA splicing and protein expression.4
350439582022The variant rs77559646 associated with aggressive prostate cancer disrupts ANO7 mRNA splicing and protein expression.4
336285982021Reduced anoctamin 7 (ANO7) expression is a strong and independent predictor of poor prognosis in prostate cancer.13
336285982021Reduced anoctamin 7 (ANO7) expression is a strong and independent predictor of poor prognosis in prostate cancer.13
321766282020The interactome of the prostate-specific protein Anoctamin 7.7
321766282020The interactome of the prostate-specific protein Anoctamin 7.7
301572912018ANO7 is associated with aggressive prostate cancer.23
301572912018ANO7 is associated with aggressive prostate cancer.23
258084432015Study of NGEP expression pattern in cancerous tissues provides novel insights into prognostic marker in prostate cancer.10
258084432015Study of NGEP expression pattern in cancerous tissues provides novel insights into prognostic marker in prostate cancer.10
239556832013Reduced expression of NGEP is associated with high-grade prostate cancers: a tissue microarray analysis.16
239556832013Reduced expression of NGEP is associated with high-grade prostate cancers: a tissue microarray analysis.16
194957502010New gene expressed in prostate: a potential target for T cell-mediated prostate cancer immunotherapy.16

Citation

Dessen P

ANO7 (anoctamin 7)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41656/haematological-explorer/gene-fusions/js/lib/zoomerang.js