Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5110
MIM: 176851
HGNC: 8728
Ensembl: ENSG00000120265
Variants:
dbSNP: 5110
ClinVar: 5110
TCGA: ENSG00000120265
COSMIC: PCMT1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Metabolism of proteins | REACTOME | R-HSA-392499 |
| Protein repair | REACTOME | R-HSA-5676934 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36639265 | 2023 | In vitro Anti-malignant Property of PCMT1 Silencing and Identification of the SNHG16/miR-195/PCMT1 Regulatory Axis in Breast Cancer Cells. | 3 |
| 37157118 | 2023 | The role of PIMT in Alzheimer's disease pathogenesis: A novel hypothesis. | 3 |
| 37535852 | 2023 | The Role of Protein-L-isoaspartyl Methyltransferase (PIMT) in the Suppression of Toxicity of the Oligomeric Form of Aβ42, in Addition to the Inhibition of Its Fibrillization. | 0 |
| 37596654 | 2023 | PCMT1 is a potential target related to tumor progression and immune infiltration in liver cancer. | 0 |
| 37899170 | 2023 | PCMT1 regulates the migration, invasion, and apoptosis of prostate cancer through modulating the PI3K/AKT/GSK-3β pathway. | 1 |
| 37953789 | 2023 | PCMT1 knockdown attenuates malignant properties by globally regulating transcriptome profiles in triple-negative breast cancer cells. | 1 |
| 38162070 | 2023 | [Prognostic Value of PCMT1 Expression in Gastric Cancer and Its Regulatory Effect on Spindle Assembly Checkpoints]. | 0 |
| 36639265 | 2023 | In vitro Anti-malignant Property of PCMT1 Silencing and Identification of the SNHG16/miR-195/PCMT1 Regulatory Axis in Breast Cancer Cells. | 3 |
| 37157118 | 2023 | The role of PIMT in Alzheimer's disease pathogenesis: A novel hypothesis. | 3 |
| 37535852 | 2023 | The Role of Protein-L-isoaspartyl Methyltransferase (PIMT) in the Suppression of Toxicity of the Oligomeric Form of Aβ42, in Addition to the Inhibition of Its Fibrillization. | 0 |
| 37596654 | 2023 | PCMT1 is a potential target related to tumor progression and immune infiltration in liver cancer. | 0 |
| 37899170 | 2023 | PCMT1 regulates the migration, invasion, and apoptosis of prostate cancer through modulating the PI3K/AKT/GSK-3β pathway. | 1 |
| 37953789 | 2023 | PCMT1 knockdown attenuates malignant properties by globally regulating transcriptome profiles in triple-negative breast cancer cells. | 1 |
| 38162070 | 2023 | [Prognostic Value of PCMT1 Expression in Gastric Cancer and Its Regulatory Effect on Spindle Assembly Checkpoints]. | 0 |
| 35033172 | 2022 | Genome-wide CRISPR/Cas9 library screen identifies PCMT1 as a critical driver of ovarian cancer metastasis. | 20 |
Citation
Dessen P
PCMT1 (protein-L-isoaspartate (D-aspartate) O-methyltransferase)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/41669/pcmt1
