PDLIM4 (PDZ and LIM domain 4)

2003-02-01 Affiliation

Identity

HGNC

PDLIM4

LOCATION

5q31.1

LOCUSID

8572

ALIAS

RIL

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 8572
MIM: 603422
HGNC: 16501
Ensembl: ENSG00000131435

Variants:

dbSNP: 8572
ClinVar: 8572
TCGA: ENSG00000131435
COSMIC: PDLIM4

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000131435	ENST00000253754	P50479
ENSG00000131435	ENST00000379018	P50479
ENSG00000131435	ENST00000379018	A0A0S2Z4N4
ENSG00000131435	ENST00000418373	C9J542

Expression (GTEx)

100

150

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
30578378	2019	Associations between polymorphisms of the PDLIM4 gene and susceptibility to osteoporotic fracture in an elderly population of Han Chinese.	4
31376371	2019	PDZ and LIM domain protein 4 suppresses the growth and invasion of ovarian cancer cells via inactivation of STAT3 signaling.	10
30578378	2019	Associations between polymorphisms of the PDLIM4 gene and susceptibility to osteoporotic fracture in an elderly population of Han Chinese.	4
31376371	2019	PDZ and LIM domain protein 4 suppresses the growth and invasion of ovarian cancer cells via inactivation of STAT3 signaling.	10
24039914	2013	Prognostic significance of EDN/RB, HJURP, p60/CAF-1 and PDLI4, four new markers in high-grade gliomas.	24
24039914	2013	Prognostic significance of EDN/RB, HJURP, p60/CAF-1 and PDLI4, four new markers in high-grade gliomas.	24
22695491	2012	Methylation of HIN-1, RASSF1A, RIL and CDH13 in breast cancer is associated with clinical characteristics, but only RASSF1A methylation is associated with outcome.	28
22695491	2012	Methylation of HIN-1, RASSF1A, RIL and CDH13 in breast cancer is associated with clinical characteristics, but only RASSF1A methylation is associated with outcome.	28
21636573	2011	Actin cytoskeleton remodeling by the alternatively spliced isoform of PDLIM4/RIL protein.	9
21636573	2011	Actin cytoskeleton remodeling by the alternatively spliced isoform of PDLIM4/RIL protein.	9
19011242	2009	Integrin alpha6beta4 controls the expression of genes associated with cell motility, invasion, and metastasis, including S100A4/metastasin.	77
19131452	2009	Genetic association study for RSV bronchiolitis in infancy at the 5q31 cytokine cluster.	26
19212833	2009	PDLIM4, an actin binding protein, suppresses prostate cancer cell growth.	24
19307596	2009	Reversion-induced LIM interaction with Src reveals a novel Src inactivation cycle.	18
19453261	2009	High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.	23

Citation

Dessen P

PDLIM4 (PDZ and LIM domain 4)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41685