PDZK1 (PDZ domain containing 1)

2003-02-01  

Identity

HGNC
PDZK1
LOCATION
1q21.1
LOCUSID
5174
ALIAS
CAP70,CLAMP,NHERF-3,NHERF3,PDZD1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 5174
MIM: 603831
HGNC: 8821
Ensembl: ENSG00000174827

Variants:

dbSNP: 5174
ClinVar: 5174
TCGA: ENSG00000174827
COSMIC: PDZK1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000174827ENST00000344770Q5T2W1
ENSG00000174827ENST00000417171Q5T2W1
ENSG00000174827ENST00000443667A0A0C4DG67
ENSG00000174827ENST00000451928Q5T2W1

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
386049992024PDZK1 suppresses TNBC development and sensitizes TNBC cells to erlotinib via the EGFR pathway.0
386193232024CHD4 and SMYD1 repress common transcriptional programs in the developing heart.2
386691032024Promoter hypomethylated PDZK1 acts as a tumorigenic gene in glioma by interacting with AKT1.2
386920102024PDZK1 is correlated with DCE-MRI perfusion parameters in high-grade glioma.0
386049992024PDZK1 suppresses TNBC development and sensitizes TNBC cells to erlotinib via the EGFR pathway.0
386193232024CHD4 and SMYD1 repress common transcriptional programs in the developing heart.2
386691032024Promoter hypomethylated PDZK1 acts as a tumorigenic gene in glioma by interacting with AKT1.2
386920102024PDZK1 is correlated with DCE-MRI perfusion parameters in high-grade glioma.0
374426062023Interaction of Human OATP1B1 with PDZK1 Is Required for Its Trafficking to the Hepatocyte Plasma Membrane.2
374426062023Interaction of Human OATP1B1 with PDZK1 Is Required for Its Trafficking to the Hepatocyte Plasma Membrane.2
360522782022HBV Infection-Related PDZK1 Plays an Oncogenic Role by Regulating the PI3K-Akt Pathway and Fatty Acid Metabolism and Enhances Immunosuppression.1
360522782022HBV Infection-Related PDZK1 Plays an Oncogenic Role by Regulating the PI3K-Akt Pathway and Fatty Acid Metabolism and Enhances Immunosuppression.1
335860762021PDZK1 induces resistance to apoptosis in esophageal adenocarcinoma cells.2
335860762021PDZK1 induces resistance to apoptosis in esophageal adenocarcinoma cells.2
314449212020Sun exposure and PDZK1 genotype modulate PDZK1 gene expression in normal skin.1

Citation

Dessen P

PDZK1 (PDZ domain containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41687/pdzk1