Identity
HGNC
LOCATION
17q23.3
LOCUSID
ALIAS
CD31,CD31/EndoCAM,GPIIA,PECA1,PECAM-1,endoCAM
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5175
MIM: 173445
HGNC: 8823
Ensembl: ENSG00000261371
Variants:
dbSNP: 5175
ClinVar: 5175
TCGA: ENSG00000261371
COSMIC: PECAM1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000261371 | ENST00000563523 | A0A075B728 |
| ENSG00000261371 | ENST00000563924 | P16284 |
| ENSG00000261371 | ENST00000564866 | A0A075B727 |
| ENSG00000261371 | ENST00000569967 | A0A075B737 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35195045 | 2023 | Elevated shear rate-induced by exercise increases eNOS ser(1177) but not PECAM-1 Tyr(713) phosphorylation in human conduit artery endothelial cells. | 2 |
| 37051650 | 2023 | CD31 as a probable responding and gate-keeping protein of the blood-brain barrier and the risk of Alzheimer's disease. | 2 |
| 37580771 | 2023 | PECAM-1 drives β-catenin-mediated EndMT via internalization in colon cancer with diabetes mellitus. | 0 |
| 37658225 | 2023 | CD31 defines a subpopulation of human adipose-derived regenerative cells with potent angiogenic effects. | 1 |
| 35195045 | 2023 | Elevated shear rate-induced by exercise increases eNOS ser(1177) but not PECAM-1 Tyr(713) phosphorylation in human conduit artery endothelial cells. | 2 |
| 37051650 | 2023 | CD31 as a probable responding and gate-keeping protein of the blood-brain barrier and the risk of Alzheimer's disease. | 2 |
| 37580771 | 2023 | PECAM-1 drives β-catenin-mediated EndMT via internalization in colon cancer with diabetes mellitus. | 0 |
| 37658225 | 2023 | CD31 defines a subpopulation of human adipose-derived regenerative cells with potent angiogenic effects. | 1 |
| 34689374 | 2022 | The expression pattern of CD10 and CD31 identifies fine fibrovascular stroma of grade 1-endometrial endometrioid carcinomas in cytology. | 1 |
| 34937389 | 2022 | Atomic Level Dissection of the Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1) Homophilic Binding Interface: Implications for Endothelial Cell Barrier Function. | 3 |
| 35917764 | 2022 | Immunohistochemical analysis of CD31 expression in myocardial tissues from autopsies of patients with ischemic heart disease. | 2 |
| 36327819 | 2022 | Colon tumor CD31 expression is associated with higher disease-free survival in patients with metabolic syndrome. | 0 |
| 34689374 | 2022 | The expression pattern of CD10 and CD31 identifies fine fibrovascular stroma of grade 1-endometrial endometrioid carcinomas in cytology. | 1 |
| 34937389 | 2022 | Atomic Level Dissection of the Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1) Homophilic Binding Interface: Implications for Endothelial Cell Barrier Function. | 3 |
| 35917764 | 2022 | Immunohistochemical analysis of CD31 expression in myocardial tissues from autopsies of patients with ischemic heart disease. | 2 |
Citation
Dessen P
PECAM1 (platelet and endothelial cell adhesion molecule 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/41689/pecam1
